DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7886 and Rnh1

DIOPT Version :9

Sequence 1:	NP_650378.1	Gene:	CG7886 / 41775	FlyBaseID:	FBgn0038248	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_001257691.1	Gene:	Rnh1 / 100360501	RGDID:	621398	Length:	492	Species:	Rattus norvegicus

Alignment Length:	189	Identity:	46/189 - (24%)
Similarity:	78/189 - (41%)	Gaps:	38/189 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 VLKLEGLPLQDGYIETIAKALADNECLESVSFRKSNIGDKGCEVVCN-----TAKYLNRIEVFDL 214
            |::|:...|.:...:.|..|:..|..|..:|.|.:.:||.|..:|..     |.|    |:...|
  Rat    63 VVRLDDCGLTEVRCKDIRSAIQANPALTELSLRTNELGDAGVGLVLQGLQNPTCK----IQKLSL 123

  Fly   215 SECGLTSKGAEHVADMLKMQKITRFTEGWEKSLRYRSVDVNTIGGLRTVLLADNPEIGDVGIRWI 279
            ..|.||..|...:.|:|:                       ::..||.:.|.||| :||.|::.:
  Rat   124 QNCSLTEAGCGVLPDVLR-----------------------SLSTLRELHLNDNP-LGDEGLKLL 164

  Fly   280 TEVLKE-DAWIKKIDMEGCGLTDIGANLILDCLELNTAITEFNVRNNEGISKFLQRSIH 337
            .|.|:: ...::|:.:|.|.||......:...|.:.....|..:.||:    |.:..||
  Rat   165 CEGLRDPQCRLEKLQLEYCNLTATSCEPLASVLRVKPDFKELVLSNND----FHEAGIH 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7886	NP_650378.1	LRR_RI	<142..320	CDD:238064	40/170 (24%)
		leucine-rich repeat	153..180	CDD:275381	6/24 (25%)
		leucine-rich repeat	181..208	CDD:275381	9/31 (29%)
		leucine-rich repeat	209..246	CDD:275381	8/36 (22%)
		leucine-rich repeat	260..285	CDD:275381	11/24 (46%)
Rnh1	NP_001257691.1	LRR_RI	37..356	CDD:238064	46/189 (24%)
		leucine-rich repeat	38..60	CDD:275380
		LRR	<46..361	CDD:227223	46/189 (24%)
		leucine-rich repeat	61..88	CDD:275380	6/24 (25%)
		leucine-rich repeat	89..113	CDD:275380	7/23 (30%)
		leucine-rich repeat	118..145	CDD:275380	8/49 (16%)
		leucine-rich repeat	146..174	CDD:275380	11/28 (39%)
		leucine-rich repeat	175..202	CDD:275380	6/26 (23%)
		leucine-rich repeat	203..231	CDD:275380	6/21 (29%)
		leucine-rich repeat	232..259	CDD:275380
		leucine-rich repeat	260..288	CDD:275380
		leucine-rich repeat	289..309	CDD:275380
		leucine-rich repeat	317..336	CDD:275380
		LRR_RI	318..>465	CDD:238064
		leucine-rich repeat	374..402	CDD:275380
		leucine-rich repeat	403..430	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810