DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7886 and si:dkey-23k10.3

DIOPT Version :9

Sequence 1:NP_650378.1 Gene:CG7886 / 41775 FlyBaseID:FBgn0038248 Length:818 Species:Drosophila melanogaster
Sequence 2:XP_009290117.1 Gene:si:dkey-23k10.3 / 100150225 ZFINID:ZDB-GENE-131126-11 Length:692 Species:Danio rerio


Alignment Length:196 Identity:47/196 - (23%)
Similarity:95/196 - (48%) Gaps:32/196 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   139 LVQAIANCVSSNKNLSVLKLEGLPLQDGYIETIAKALADNEC-LESVSFRKSNIGDKGCEVVCNT 202
            ||.|:.:..|..:||.   |.|..|:...|:.:::.|....| ||::..|..|:.|:.|..:.:.
Zfish   368 LVSALRSNPSHLRNLD---LSGNNLECFEIKLLSEVLESPYCKLETLKLRNCNLKDEECVSLASA 429

  Fly   203 AKY-LNRIEVFDLSECGLTSKGAEHVADMLKMQ-KITRFTEGWEKSLRYRSVDVNTIG-GLRTVL 264
            .:. ::::...||||..|...|.:  |...::: .:::|     .:||:.:..:...| |:...:
Zfish   430 LRLKISKLRELDLSENKLGDSGVK--AFFAELEGHLSKF-----DALRFVNCGLTDEGCGVLASV 487

  Fly   265 LADNP-----------EIGDVGIRWITEVLKEDAW-IKKIDMEGCGLTDIGANLILDCLELNTAI 317
            |:.||           ::.|.|::.:::.|::... ::.:.:.||||||.|      |..|.:|:
Zfish   488 LSSNPSHLKELDLSGNKVEDSGVKMLSDGLEDYCCRLETLKLVGCGLTDEG------CASLASAL 546

  Fly   318 T 318
            |
Zfish   547 T 547

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7886NP_650378.1 LRR_RI <142..320 CDD:238064 45/193 (23%)
leucine-rich repeat 153..180 CDD:275381 6/26 (23%)
leucine-rich repeat 181..208 CDD:275381 6/27 (22%)
leucine-rich repeat 209..246 CDD:275381 8/37 (22%)
leucine-rich repeat 260..285 CDD:275381 6/35 (17%)
si:dkey-23k10.3XP_009290117.1 LRR_RI 59..360 CDD:238064
leucine-rich repeat 60..88 CDD:275380
leucine-rich repeat 89..117 CDD:275380
leucine-rich repeat 118..146 CDD:275380
leucine-rich repeat 147..175 CDD:275380
leucine-rich repeat 176..203 CDD:275380
leucine-rich repeat 205..233 CDD:275380
leucine-rich repeat 234..262 CDD:275380
leucine-rich repeat 263..291 CDD:275380
LRR_RI 291..591 CDD:238064 47/196 (24%)
leucine-rich repeat 292..320 CDD:275380
leucine-rich repeat 350..378 CDD:275380 3/9 (33%)
leucine-rich repeat 408..436 CDD:275380 6/27 (22%)
leucine-rich repeat 437..465 CDD:275380 7/29 (24%)
leucine-rich repeat 469..494 CDD:275381 7/24 (29%)
leucine-rich repeat 495..523 CDD:275381 3/27 (11%)
leucine-rich repeat 524..552 CDD:275381 11/30 (37%)
leucine-rich repeat 553..581 CDD:275381
leucine-rich repeat 582..610 CDD:275381
LRR_RI 609..635 CDD:197686
leucine-rich repeat 611..639 CDD:275381
leucine-rich repeat 640..668 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4308
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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