Protein Alignment Cad88C and cdhr2

DIOPT Version :10

• Sequence 1: NP_731930.3
• Gene: Cad88C / 41774
• FlyBaseID: FBgn0038247
• Length: 1981
• Species: Drosophila melanogaster
• Sequence 2: XP_031754706.1
• Gene: cdhr2 / 100491782
• XenbaseID: XB-GENE-1004777
• Length: 1320
• Species: Xenopus tropicalis
• Alignment Length: 1209
• Identity: 334/1209 - (27%)
• Similarity: 555/1209 - (45%)
• Gaps: 207/1209 - (17%)

  Fly    41 IQVII-LTTLISLVASNRPPRFAIDGQSEIVLRLKESPE-TKVGTLIYTLKGYDPDNDPLTFGKR 103
            ||::: |..::::.:.|..|.||.:..|..:      || |.:|..::.:...|.||||||: ..
 Frog    11 IQLLLPLVFMVTVSSQNTAPEFASNMTSAFI------PEDTPLGKCVFWIVARDADNDPLTY-SM 68

  Fly   104 NSHDSEIIRIENTGGNEAKIFLAKELDRELQDEYAIVLTLTDSHYSDHNYVTQSFLLLVEDINDN 168
            ...||....:....|   ::.||..||.|.:::...::.:.|   ..:..|.:.|.::|||.|||
 Frog    69 EGQDSYYFNVNLMTG---EVQLALPLDYESKNKLNTMIKVQD---EINRPVIRQFPVIVEDRNDN 127

  Fly   169 VPTFL--PYQNAI--EIPEGSAPGVVSTLEATDADEGAYGQVVYYLQELDGD----NDVFSIATH 225
            .|.||  ||:.:|  :.|.||   :|.::.|.|.|:.....|.|.:.|:..:    |::|.|..:
 Frog   128 DPVFLGIPYEASIREDQPLGS---IVFSVSAVDFDDDGRVPVTYSIDEIIPNDLQSNNLFYILLN 189

  Fly   226 QGKGILRLQKELDYERKSL-YQLRVLAIDRA----NQGPINTGTAAILVKVKDLEDQPPEFVEVQ 285
               |.:.|...|:|..||: ||:.:.|.|:.    |.....:..|.:.:||.||.|..|:|:...
 Frog   190 ---GSIILNDTLNYNEKSIFYQMTINATDKGGLFHNHFMYRSTLAYVSLKVIDLPDLDPQFINAP 251

  Fly   286 AVARIAEDAPVGTKVLRVRAIDGDRGINNPIAYSLE---ANDLFDINPHTGIVHTLTKLDRE--- 344
            ....|.|:..:||.:.||.|||||||||:.|.||::   .:.|||||..:|.:....|:|||
 Frog   252 YSVSIEENIALGTTIFRVTAIDGDRGINDEIQYSIQDSSRHGLFDINSKSGEIFVTAKIDREALV 316

  Fly   345 EQSDQVNGAHILRISATELSKS-NTQMAPTTVRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQT 408
            :..:||    :|.:.|.|.:.: |.:.|.:|  |.|||.|.|:||..|.|    |.||:::...:
 Frog   317 QDGEQV----LLTVMAQEKNLNVNAEKATST--TTVTVRVLDINDNKPNF----YNCEIDDCDFS 371

  Fly   409 NTP-LNFIDE------------EVQNVVFDHDEGNNGTFRLFL-DPPNDLFEIVPELAVNEANFM 459
            ..| |:|:.|            :::....|.|:..||.|.|:| ....|.|.:.|....|.....
 Frog   372 AAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDKDKNGNFNLYLRGKDQDCFTVSPARVQNTGLIQ 436

  Fly   460 LRVKNSKSLDFEQFTEVNFTIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYNASVLENSE 524
            :.||:|.::|:|:..::...|.|.:.......|.|.|.|.|.|.||:.|||||..|...|:||..
 Frog   437 VLVKDSVAIDYEKVHQMEVEIVANDTGLQDCCSYATVTIDIIDINDHTPEFSQDTYYLEVMENCP 501

  Fly   525 QDTIITHVQAVDVDSGDYGTMGIRYTNLRGGIAHLLNLNPITGVITIKQAGGTAFDREIISRHYL 589
            ..|.|..:.|.|:|||:.|.  |.|..|...|..:.:::..:|.|.  ...|...|||..|.:|.
 Frog   502 DGTQIGTITATDLDSGELGK--ITYQLLPESIRQIFHVDSDSGEII--AVNGNLLDRERRSLYYA 562

  Fly   590 TVEAIDNAGQGNRNTAQIIVDILDVNDNAPTFPQRQYETKLLENQAEFETPLQLEARDADLNGTE 654
            |::|.|  |.....||.:.:.|||.||..|| ....|...:.||..:..  :|:||.|||...|.
 Frog   563 TLQAAD--GLNATGTALLEITILDENDEIPT-AIGSYNIFVNENTDDVR--IQIEAFDADEPNTN 622

  Fly   655 NSQVTYEIVEGLYRSNFTIDPQSGLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIREIDLLVRAR 719
            ||::.:|::..:..|||:::..:||:..:...|.|.:        |....|.     |.|.|:..
 Frog   623 NSRIEFELLPSVLSSNFSVNVTTGLITSIGPLDREAI--------DEKDNGC-----IVLTVKLY 674

  Fly   720 DSGIPMLSTVVPVLIYVQDVNDNAPIFQQSFYAKTVPED-LPGGSSVLQVTAIDRDGSAPNNVVV 783
            |.|:|.||:.|.|.|.|:|:|||.|:|.::.|...|.|. :.....:|.|:  |:|.:..||.|.
 Frog   675 DLGVPSLSSEVNVTINVEDLNDNVPVFSKTVYDFFVNESTIAAQVGILLVS--DQDQTELNNRVS 737

  Fly   784 YRIQTGAGDKFIINSE-------TGVISVAHGANLDPDLT---ESKRSLYTLSVIALDGGLGNSQ 838
            :||..|....|||.::       .|::|      ||||:.   |:::: |||.:.|.|.||....
 Frog   738 FRISQGGSGNFIIRNQKVESGLYNGILS------LDPDVMLDYETQKN-YTLIIEAQDNGLHGVS 795

  Fly   839 LMTTCTVNISIQDVNNKPPVL--KEMPALQILENTPVG-TLVYRIQATDLDHKAILRYKLNPEHC 900
            ...|.|.::.:.|:|::||.:  ..:..|.:|||..|| .|:..::|.|.|....|.::.....|
 Frog   796 HTATATASVQVLDLNDEPPYVDPSSLNNLFLLENRTVGLELLTTLKAHDPDTIHELEFQALSLQC 860

  Fly   901 EGRTEEGALVKSSEYDFL-----GAFEVDSIEGTLKVVKLLDRERVEHIKLAITVEDLAAAKGRQ 960
               .:.|..:.:..||::     |...|:..|       ::|.|..:.:.:.:.|||.....|.:
 Frog   861 ---FKNGNDIGNICYDWIWLAPNGELFVNDTE-------VVDYELCDVMVMMLRVEDKLTLIGDR 915

  Fly   961 IAEG-FLSIQVLDENDNNPKF------------------RLPFYRQSITENSINGAMIVNVLASD 1006
            .::. .|.:.:||.|||.|:|                  ::...:.:..::.:|..:..::.:.:
 Frog   916 YSKNESLRVDILDVNDNAPEFLDVDEVFVVVPDVAPIDYQVALVKATDKDSGLNAVLKFSIASVE 980

  Fly  1007 VDKNRTITYALEGNPTYRSLMHL---------DPQTGEIVVASKIDHEQHQWLNFSVRATDSGIP 1062
            .         :.|:.| |.|:::         :...|.|.|||.:|            ||..|
 Frog   981 F---------ISGDST-RPLLNIFTIVTTSEKEIYQGSIRVASSLD------------ATLKG-- 1021

  Fly  1063 ARSSLVDVYITVLDENDNNPYFVGGSKNYTISENAAPGTRVATLQAGDADSGDFGKITFLMDRIS 1127
                  :..:||:.|:..||              :...|||..:.|.|    :..::|....:.:
 Frog  1022 ------NYRVTVIAEDSGNP--------------SLTATRVLDIFAVD----ESYRVTLKFSKTA 1062

  Fly  1128 SQGKFTIDADTGVLTVADRLD------RESKDSYNLVIE 1160
            .:.:.|.:.....||:|.:..      ::.:.|..::|:
 Frog  1063 DEVRETSEEIKRALTMATKATVYVAQIKDLEPSSKMIIQ 1101

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cad88C	NP_731930.3	Cadherin_repeat	76..168	CDD:206637	26/92 (28%)
		Cadherin_repeat	179..276	CDD:206637	30/107 (28%)
		Cadherin_repeat	287..388	CDD:206637	42/107 (39%)
		Cadherin_repeat	397..506	CDD:206637	32/122 (26%)
		Cadherin_repeat	514..617	CDD:206637	34/102 (33%)
		Cadherin_repeat	625..742	CDD:206637	36/116 (31%)
		Cadherin_repeat	751..853	CDD:206637	33/112 (29%)
		Cadherin_repeat	865..976	CDD:206637	28/117 (24%)
		Cadherin_repeat	985..1080	CDD:206637	17/103 (17%)
		Cadherin_repeat	1090..1191	CDD:206637	12/77 (16%)
		CA	1221..1302	CDD:214520
		Cadherin_repeat	1312..1409	CDD:206637
		Cadherin_repeat	1418..>1502	CDD:206637
		Cadherin_repeat	1617..1710	CDD:206637
cdhr2	XP_031754706.1	Cadherin_repeat	38..127	CDD:206637	27/101 (27%)
		Cadherin_repeat	135..242	CDD:206637	32/112 (29%)
		Cadherin_repeat	251..>332	CDD:206637	33/84 (39%)
		Cadherin_repeat	381..483	CDD:206637	26/101 (26%)
		Cadherin_repeat	491..587	CDD:206637	33/101 (33%)
		Cadherin_repeat	595..697	CDD:206637	36/116 (31%)
		Cadherin_repeat	705..811	CDD:206637	33/114 (29%)
		Cadherin_repeat	941..1045	CDD:206637	22/147 (15%)