Protein Alignment put and tgfbr1a

DIOPT Version :10

• Sequence 1: NP_001262575.1
• Gene: put / 41772
• FlyBaseID: FBgn0003169
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001032772.2
• Gene: tgfbr1a / 560578
• ZFINID: ZDB-GENE-051120-75
• Length: 500
• Species: Danio rerio
• Alignment Length: 539
• Identity: 172/539 - (31%)
• Similarity: 257/539 - (47%)
• Gaps: 102/539 - (18%)

  Fly     5 DLLYLTAQLTLVCCLIGIHGSILPGSHGII-ECEHFDEKMCNTTQQC-----------ETRIEHC 57
            |:..||::..|:..|:   .|:...:.|:: .||....:.||||..|           .|:...|
Zfish     7 DVASLTSRSLLLALLV---LSVTHEAQGLLCYCERCVNRSCNTTGLCFAVIAKSSGQTVTQERQC 68

  Fly    58 KMEADKFPSCYVLWSVNETTGILRIKMKGCFTDMHECNQTECVTSAEPRQGNIHFCCCKGSRCNS 122
            ..:.|.:|               |.:...|                .|.....|..||....||.
Zfish    69 IQQDDLYP---------------RDRPFQC----------------APSNNGKHPYCCNTHMCNK 102

  Fly   123 NQKYIKSTTEATTQVPKEKTQDGSNL---IYIYIGTSVFSVLMVIVGMGLLLY--RRRKQAHFNE 182
            |.|.|       .::|:.:.|..|.:   ..|.:...|.|.::|     ||.|  ..|...| :.
Zfish   103 NPKVI-------PELPEAEPQSMSPIALAAMIAVPICVLSFVLV-----LLFYMCHNRSIIH-HR 154

  Fly   183 IPTHE-------------------AEITNSS-----PLLSNRPIQ----LLEQKASGRFGDVWQA 219
            :|:.|                   .::|.|.     |||..|.|.    |.|....||||:||:.
Zfish   155 VPSEEDPTMDHPFLADGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIILQESIGKGRFGEVWRG 219

  Fly   220 KLNNQDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLGVEKHMDK---PEYWLISTYQHNG 281
            :...::||||||..:|:.||..|.:||:...:||.|||.|:..: :.|.   .:.||:|.|..:|
Zfish   220 RWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAAD-NKDNGTWTQLWLVSDYHEHG 283

  Fly   282 SLCDYLKSHTISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSDLTAC 346
            ||.|||..:|::...:.:::.|.|:||||||.||..  |.| ||:|||||.||||:|:|.:.|.|
Zfish   284 SLFDYLNRYTVTVEGMIKLSLSTASGLAHLHMEIVG--TQG-KPAIAHRDLKSKNILVKKNGTCC 345

  Fly   347 IADFGLAMIFQPGKPCGD--THGQVGTRRYMAPEVLEGAINFNR-DAFLRIDVYACGLVLWEMVS 408
            |||.|||:.........|  .:.:|||:||||||||:.:||... ::|.|.|:||.|||.||:..
Zfish   346 IADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMRHFESFKRADIYALGLVFWEIAR 410

  Fly   409 RCDFAGPVGEFQLPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWRAHPGLNVFCDTMEECWDHD 473
            ||...|...::|||:...:...||:::::..|..:||||.:.|.|::...|.|....|.|||..:
Zfish   411 RCSIGGIHEDYQLPYYDLVPSDPSVEDMKRVVCDQKLRPNIPNRWQSCEALRVMAKIMRECWYAN 475

  Fly   474 AEARLSSSCVMERFAQLNK 492
            ..|||::..|.:..:||::
Zfish   476 GGARLTALRVKKSLSQLSQ 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
put	NP_001262575.1	TFP_LU_ECD_ACVR2	33..125	CDD:467135	20/103 (19%)
		STKc_ACVR2	206..493	CDD:270955	121/293 (41%)
tgfbr1a	NP_001032772.2	TFP_LU_ECD_ALK5	32..102	CDD:467067	18/100 (18%)
		Psg1	<101..154	CDD:464218	16/65 (25%)
		TGF_beta_GS	173..200	CDD:462503	7/26 (27%)
		STKc_TGFbR1_ACVR1b_ACVR1c	206..493	CDD:271045	120/290 (41%)