Protein Alignment put and Acvr2b

DIOPT Version :10

• Sequence 1: NP_001262575.1
• Gene: put / 41772
• FlyBaseID: FBgn0003169
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_038936802.1
• Gene: Acvr2b / 25366
• RGDID: 2028
• Length: 545
• Species: Rattus norvegicus
• Alignment Length: 512
• Identity: 236/512 - (46%)
• Similarity: 321/512 - (62%)
• Gaps: 50/512 - (9%)

  Fly    35 ECEHFDE--KMCNTTQQCETRIEHCKMEADKFPSCYVLWSVNETTGILRIKMKGCFTDMHEC-NQ 96
            ||.:::.  ::..|.|   :.:|.|:.|.||...||..|  ..::|.:.:..|||:.|...| ::
  Rat    37 ECIYYNANWELERTNQ---SGLERCEGEQDKRLHCYASW--RNSSGTIELVKKGCWLDDFNCYDR 96

  Fly    97 TECVTSAEPRQGNIHFCCCKGSRCNSNQKYIKSTTEATTQVPKEKTQDGSNLIYIYIGTSVFSV- 160
            .|||.:.|..|  ::||||:|:.|  |:::.........:|..|.......|:.: :..|:..:
  Rat    97 QECVATEENPQ--VYFCCCEGNFC--NERFTHLPEPGGPEVTYEPPPTAPTLLTV-LAYSLLPIG 156

  Fly   161 -LMVIVGMGLLLYRRRKQAHFNEIPTHEAEITN-------------------------SSPLLSN 199
             |.:||.:...:||.||.. :..:..||.....                         .|||:..
  Rat   157 GLSLIVLLAFWMYRHRKPP-YGHVDIHEVRQCQRGGGGRDGCADSFKLLLFQDPGPPPPSPLVGL 220

  Fly   200 RPIQLLEQKASGRFGDVWQAKLNNQDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLGVEK 264
            :|:||||.||.||||.||:|:|.|..||||||.:|:|:||.:|.:|:..|.|:|.|:|:|:..||
  Rat   221 KPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEK 285

  Fly   265 HMD--KPEYWLISTYQHNGSLCDYLKSHTISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSI 327
            ...  :.|.|||:.:...|||.||||.:.|:|.|||.:||:|:.||::|||::|..:.:|.||||
  Rat   286 RGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSI 350

  Fly   328 AHRDFKSKNVLLKSDLTACIADFGLAMIFQPGKPCGDTHGQVGTRRYMAPEVLEGAINFNRDAFL 392
            ||||||||||||||||||.:||||||:.|:||||.||||||||||||||||||||||||.|||||
  Rat   351 AHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFL 415

  Fly   393 RIDVYACGLVLWEMVSRCDFA-GPVGEFQLPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWRAH 456
            |||:||.||||||:||||..| |||.|:.||||.|:|..|||:|:||.||.||:||.:.:.|..|
  Rat   416 RIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKH 480

  Fly   457 PGLNVFCDTMEECWDHDAEARLSSSCVMERFAQLNKYPSTQL------LIKNHTNID 507
            |||...|.|:|||||||||||||:.||.||.:.:.:..::..      |:.:.||:|
  Rat   481 PGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNSSTSDCLVSLVTSVTNVD 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
put	NP_001262575.1	TFP_LU_ECD_ACVR2	33..125	CDD:467135	30/92 (33%)
		STKc_ACVR2	206..493	CDD:270955	182/289 (63%)
Acvr2b	XP_038936802.1	TFP_LU_ECD_ACVR2B	35..125	CDD:467152	30/96 (31%)
		STKc_ACVR2b	227..517	CDD:271042	182/289 (63%)