Protein Alignment put and daf-1

DIOPT Version :10

• Sequence 1: NP_001262575.1
• Gene: put / 41772
• FlyBaseID: FBgn0003169
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001023159.1
• Gene: daf-1 / 176829
• WormBaseID: WBGene00000897
• Length: 669
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 142/571 - (24%)
• Similarity: 235/571 - (41%)
• Gaps: 145/571 - (25%)

  Fly    27 LPGSHGIIECEH-FDEKMCNTTQQC------ETRIEHCKMEADKFPSCYVLWSVNETTGILRIKM 84
            :||...:.|.:. |.|..|.|...|      ...|.|.....:|        ||.:.
 Worm    72 VPGIEFLNETDRSFYENTCYTDGSCYQSARPSPEISHFGCMDEK--------SVTDE-------- 120

  Fly    85 KGCFTDMHECNQTECVTSAEPRQGNIHFCCCKGSRCNSNQKYIKSTTEATTQVPKEKTQDGSNLI 149
                |:.|:.....|..:.:.....:..||.||:.|         ..|....:.....|..:.||
 Worm   121 ----TEFHDTAAKVCTNNTKDPHATVWICCDKGNFC---------ANETIIHLAPGPQQSSTWLI 172

  Fly   150 YIYIGTSVFSVLMVIVGMGLLLYRRRKQAHF------------------NEIP------------ 184
            ...:....|   :|::|:.:.|.|:..:|.|                  |.:|
 Worm   173 LTILALLTF---IVLLGIAIFLTRKSWEAKFDWYIRFKPKPGDPLRETENNVPMVTMGDGAGSSV 234

  Fly   185 -----------THEAEITNSSP--LLSNR----------------------------PIQLLEQK 208
                       |......||.|  ::.|.                            .|:|..:.
 Worm   235 PEVAPIEQQGSTMSTSAGNSFPPGIMPNNMKDMLDVLEETSGSGMGPTTLHKLTIGGQIRLTGRV 299

  Fly   209 ASGRFGDVWQAKLNNQDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLGVEKHMDK---PE 270
            .|||||:|.:.....:.||||:|...::.::..|.:|::...:||||:|.::|.:: :|.   .|
 Worm   300 GSGRFGNVSRGDYRGEAVAVKVFNALDEPAFHKETEIFETRMLRHPNVLRYIGSDR-VDTGFVTE 363

  Fly   271 YWLISTYQHNGSLCDYLKSHTISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSK 335
            .||::.|..:|||.|:|..:|::......:..|.|:|||.||.:|..|| :..||::||||.|||
 Worm   364 LWLVTEYHPSGSLHDFLLENTVNIETYYNLMRSTASGLAFLHNQIGGSK-ESNKPAMAHRDIKSK 427

  Fly   336 NVLLKSDLTACIADFGLAMIFQPGKP-------CGDTHGQVGTRRYMAPEVLEGAINFN-RDAFL 392
            |:::|:|||..|.|.||::    .||       ..:.:.:.||.||:|||:|...:.|. .:::.
 Worm   428 NIMVKNDLTCAIGDLGLSL----SKPEDAASDIIANENYKCGTVRYLAPEILNSTMQFTVFESYQ 488

  Fly   393 RIDVYACGLVLWEMVSRCDFAGPVGEFQLPFEAELGL--------RPSLDEVQESVVMKKLRPRL 449
            ..|||:..||:||.:.||: .|.|    ||.||...:        .|...::.:.|..::|||..
 Worm   489 CADVYSFSLVMWETLCRCE-DGDV----LPREAATVIPYIEWTDRDPQDAQMFDVVCTRRLRPTE 548

  Fly   450 LNSWRAHPGLNVFCDTMEECWDHDAEARLSSSCVMERFAQLNKYPSTQLLI 500
            ...|:.||.:....:.::.||:.:..||.:|....:|..:     ..|||:
 Worm   549 NPLWKDHPEMKHIMEIIKTCWNGNPSARFTSYICRKRMDE-----RQQLLL 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
put	NP_001262575.1	TFP_LU_ECD_ACVR2	33..125	CDD:467135	19/98 (19%)
		STKc_ACVR2	206..493	CDD:270955	98/305 (32%)
daf-1	NP_001023159.1	TFP	55..152	CDD:480272	20/99 (20%)
		STKc_TGFbR_I	297..589	CDD:270958	98/307 (32%)