Protein Alignment put and Bmpr1a

DIOPT Version :10

• Sequence 1: NP_001262575.1
• Gene: put / 41772
• FlyBaseID: FBgn0003169
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_033888.2
• Gene: Bmpr1a / 12166
• MGIID: 1338938
• Length: 532
• Species: Mus musculus
• Alignment Length: 552
• Identity: 171/552 - (30%)
• Similarity: 259/552 - (46%)
• Gaps: 99/552 - (17%)

  Fly     7 LYLTAQLTLVCCLIGIHGSILPGSHGIIECEHFDEKMCNTTQQCETRIEHCKME-------ADKF 64
            ||...:|...|..|..|          ::.::.|..:..|..:.:  ::..|.|       .|..
Mouse     4 LYTYIRLLGACLFIISH----------VQGQNLDSMLHGTGMKSD--LDQKKPENGVTLAPEDTL 56

  Fly    65 P--SCYVLW-----SVNETTGILRIKMKGCFTDMHECNQ--TECVTSAEPRQGNIHFC------- 113
            |  .||...     ::|.|.    |....||..:.|.:|  |...:.....:|:...|
Mouse    57 PFLKCYCSGHCPDDAINNTC----ITNGHCFAIIEEDDQGETTLTSGCMKYEGSDFQCKDSPKAQ 117

  Fly   114 ------CCKGSRCNSNQKYIKSTTEATTQVPKEKTQDGS-NLIYIYIGTSVFSVLMVIVGMGLLL 171
                  ||:.:.||   :|::.|.......|   ..||| ..:.:.|..:|..|.|:|.. ....
Mouse   118 LRRTIECCRTNLCN---QYLQPTLPPVVIGP---FFDGSIRWLVVLISMAVCIVAMIIFS-SCFC 175

  Fly   172 YRR-----RKQAHFNE--------IPTHEA-----EITNSS------PLLSNR----PIQLLEQK 208
            |:.     ..:..:|.        ||..|:     :.:.||      |||..|    .||::.|.
Mouse   176 YKHYCKSISSRGRYNRDLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAKQIQMVRQV 240

  Fly   209 ASGRFGDVWQAKLNNQDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLG--VEKHMDKPEY 271
            ..||:|:||..|...:.||||:|...|:.||..|.:||:...|||.|||.|:.  ::......:.
Mouse   241 GKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQL 305

  Fly   272 WLISTYQHNGSLCDYLKSHTISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKN 336
            :||:.|..||||.|:||..|:....|.::|.|.|.||.|||.||..  |.| ||:|||||.||||
Mouse   306 YLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYG--TQG-KPAIAHRDLKSKN 367

  Fly   337 VLLKSDLTACIADFGLAMIFQPGKPCGDT-------HGQVGTRRYMAPEVLEGAINFNR-DAFLR 393
            :|:|.:.:.||||.|||:.|.     .||       :.:|||:||||||||:.::|.|. ..::.
Mouse   368 ILIKKNGSCCIADLGLAVKFN-----SDTNEVDIPLNTRVGTKRYMAPEVLDESLNKNHFQPYIM 427

  Fly   394 IDVYACGLVLWEMVSRCDFAGPVGEFQLPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWRAHPG 458
            .|:|:.||::|||..||...|.|.|:|||:...:...||.::::|.|.:|:|||.:.|.|.:...
Mouse   428 ADIYSFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWNSDEC 492

  Fly   459 LNVFCDTMEECWDHDAEARLSSSCVMERFAQL 490
            |......|.|||.|:..:||::..:.:..|::
Mouse   493 LRAVLKLMSECWAHNPASRLTALRIKKTLAKM 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
put	NP_001262575.1	TFP_LU_ECD_ACVR2	33..125	CDD:467135	22/120 (18%)
		STKc_ACVR2	206..493	CDD:270955	119/295 (40%)
Bmpr1a	NP_033888.2	TFP_LU_ECD_BMPR1A	57..140	CDD:467132	19/89 (21%)
		Mediates specificity for BMP ligand. /evidence=ECO:0000250	107..109		0/1 (0%)
		TGF_beta_GS	205..232	CDD:462503	6/26 (23%)
		STKc_BMPR1a	238..524	CDD:271122	119/293 (41%)