DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment put and LOC100331938

DIOPT Version :9

Sequence 1:	NP_001262575.1	Gene:	put / 41772	FlyBaseID:	FBgn0003169	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_002667626.1	Gene:	LOC100331938 / 100331938	-ID:	-	Length:	511	Species:	Danio rerio

Alignment Length:	499	Identity:	237/499 - (47%)
Similarity:	327/499 - (65%)	Gaps:	33/499 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SHGII---ECEHFDEKMCNTTQQCETRIEHCKMEADKFPSCYVLWSVNETTGILRIKMKGCFTDM 91
            ||..:   ||.::::.. .|.:..::..|.|:.|.||...||..|.  .:||.:|:..|||:.|.
Zfish    17 SHAEVATRECVYYNDNW-RTEKTNQSGFERCEGEKDKRLHCYASWL--NSTGTIRLVKKGCWLDD 78

  Fly    92 HEC-NQTECVTSAEPRQGNIHFCCCKGSRCNSNQKYIKSTTEATTQVPKEKTQDGSNLIYIYIGT 155
            ..| ::.|||.:.|..|  :.||||:|:.|  |:|:..........|..:..|.|.:|    .|.
Zfish    79 FNCYDRQECVATEESPQ--VFFCCCEGNYC--NEKFTHLPEAIAPAVKIQPPQPGPSL----FGI 135

  Fly   156 SVFSVL-MVIVGMGLLL----YRRRKQAHFNEIPTHEAEITNSSPLLSNRPIQLLEQKASGRFGD 215
            .|:|:| :.|:.:.|:|    |.:||..:.:.....:|.:...|||:..:|:||||.||.||||.
Zfish   136 LVYSLLPLAILSLALVLACWTYHQRKPPYRHVDIGQDAGLPPPSPLVGLKPLQLLELKARGRFGC 200

  Fly   216 VWQAKLNNQDVAVKIFRMQEKESWTTEHDIYKLPRMRHPNILEFLGVEKHMD--KPEYWLISTYQ 278
            ||:|:|.::.||||||.:|:|:||..|.|||.....:|.|||.::..||...  :.|.||::.:.
Zfish   201 VWKAQLLSEYVAVKIFPIQDKQSWQNERDIYLTEGFKHENILHYISAEKRGTNLQMELWLVTEFH 265

  Fly   279 HNGSLCDYLKSHTISWPELCRIAESMANGLAHLHEEIPASKTDGLKPSIAHRDFKSKNVLLKSDL 343
            ..|||.||||.:.:|||:||.|:.||:.|||:|||::| .:.:|.||:||||||||||||||.||
Zfish   266 ERGSLTDYLKGNVVSWPQLCHISASMSRGLAYLHEDLP-YRAEGPKPAIAHRDFKSKNVLLKMDL 329

  Fly   344 TACIADFGLAMIFQPGKPCGDTHGQVGTRRYMAPEVLEGAINFNRDAFLRIDVYACGLVLWEMVS 408
            ||.|||||||:.|:||||.||||||||||||||||||||||||.||:|||||:||.||||||:||
Zfish   330 TAVIADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDSFLRIDMYALGLVLWELVS 394

  Fly   409 RCDFA-GPVGEFQLPFEAELGLRPSLDEVQESVVMKKLRPRLLNSWRAHPGLNVFCDTMEECWDH 472
            ||..: |||||:|||||.|:|..|||:::|::||.||:||...:.|..|.||:..|:|:||||||
Zfish   395 RCTASDGPVGEYQLPFEEEVGQHPSLEDLQDAVVHKKMRPVFKDCWVKHQGLSQLCETIEECWDH 459

  Fly   473 DAEARLSSSCVMERFAQLNKYPST---------QLLIKNHTNID 507
            |||||||:.||.||.:.::|..:|         ..::.:|::.|
Zfish   460 DAEARLSAGCVEERISTISKSNNTLNTSTSECLLSMLTSHSDTD 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
put	NP_001262575.1	Activin_recp	38..126	CDD:279413	29/88 (33%)
		STKc_ACVR2	206..493	CDD:270955	177/289 (61%)
		S_TKc	210..479	CDD:214567	168/271 (62%)
LOC100331938	XP_002667626.1	Activin_recp	36..114	CDD:279413	29/83 (35%)
		PKc_like	191..480	CDD:304357	177/289 (61%)
		S_TKc	195..467	CDD:214567	169/272 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	274	1.000	Domainoid score	I1736
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	440	1.000	Inparanoid score	I1635
OMA	1	1.010	-	-		QHG49534
OrthoDB	1	1.010	-	-		D191771at33208
OrthoFinder	1	1.000	-	-		FOG0001838
OrthoInspector	1	1.000	-	-		otm25421
orthoMCL	1	0.900	-	-		OOG6_104478
Panther	1	1.100	-	-	LDO	PTHR23255
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.980