Protein Alignment stumps and Pik3ap1

DIOPT Version :9

• Sequence 1: NP_731923.2
• Gene: stumps / 41770
• FlyBaseID: FBgn0020299
• Length: 1220
• Species: Drosophila melanogaster
• Sequence 2: XP_038965054.1
• Gene: Pik3ap1 / 294048
• RGDID: 1307744
• Length: 896
• Species: Rattus norvegicus
• Alignment Length: 1069
• Identity: 234/1069 - (21%)
• Similarity: 383/1069 - (35%)
• Gaps: 304/1069 - (28%)

  Fly   236 SASGFLGSPGYNMDDILIITAKHSERAYLRATFLKNHFDKITKQRGRKPFNFLHIKIDDGPFSEE 300
            :|||:    |:.. ||||..:..:|.   ...:|::.|....:.|.:|...:.  .:.|..||.:
  Rat     2 AASGW----GWGC-DILIFYSPDAEE---WCQYLQDLFVSCRQVRSQKIQTYR--LVPDACFSSQ 56

  Fly   301 IAHKYQNTALQIVILCPALLALPHSFLMTQLSAIIR-----VEKVLAILLDVSEEKVKEMHKSAL 360
            ....:::....:|:|...|:   ..|:...|..:::     .::|:.:|..|...  .|..::..
  Rat    57 DLSVFRDARCVLVLLSAGLV---ECFVQPGLLPVLQRACHPPQRVVRLLCGVQPN--DEDFQAFF 116

  Fly   361 PSYYKWRRCVVRDNDQVQISNILGIATDILG------------RALCQRP-------PCQDSSGG 406
            |.:..|:.....|..:..::.:....::..|            |||   |       |.:.|.|
  Rat   117 PDWAHWQELTCDDEPETYLAAVRKAISEDSGCDSVTDTEPEDERAL---PFSKHTDLPLETSPG- 177

  Fly   407 GGGGLSRSFSSCTEGFTVLPKKVKLGQNKVVALLAEPLEKNDTLKLQVEKSGE---LIELRNFKC 468
                         ....|.|.:::.|....|.::.. .:.::.:..:||.|.|   .:.:.. ..
  Rat   178 -------------NLMVVQPDRIRCGAETTVYVIVR-CKLDEKVSTEVEFSPEDSPSVRMEG-TL 227

  Fly   469 RNPYTLQFNIPEACMEISTMIEIRIEKNNKSLGARPIKCESRLRELEQLLRIEDSPIEFMCHALG 533
            .|.||:....|:..   |..:.:::...:..:....|...:.:.|:..||....:|:||||.|..
  Rat   228 ENEYTVSVKAPDLS---SGNVSLKVYSGDLVVCETTISYYTDMEEIGNLLSSAANPVEFMCQAFK 289

  Fly   534 IGPVERDALDQHLLQCFQRNMPPN-FHLLSGPSERQPHFFTRLESSPEEYPTLLHFAARWGLNRL 597
            |.|...:.||:.|.:..:.|:|.: .||.......:....|  ....||.||||||||::||..|
  Rat   290 IVPYNTETLDKLLTESLKNNIPASGLHLFGINQLEEDDMMT--NQRDEELPTLLHFAAKYGLKNL 352

  Fly   598 CIQLMECPGGDTACGVRNCAGRTPAELAEQEGHHKLAQNIVSFAEFHEL---------------- 646
            ...|:.|||...|..|.|..|..|..:||:.|...|.|.|..:.|..::
  Rat   353 TALLLTCPGALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEYVETVDMLKSHIKEELMQGEEAD 417

  Fly   647 ---TTMYH-----YFKGVTPPG------ES----CPKPSANVVIE------AHPVKAGKTNKPPK 687
               .:|.|     ..|....||      ||    .|..:.::.:|      .:||.....::|.|
  Rat   418 DVYESMAHLSTDLLMKCSLNPGCDDELYESMAAFAPAATEDLYVEMLQASAGNPVSGESFSRPTK 482

  Fly   688 ELPTAEYMEMSS----GSERENTPEVRTKTETLAISNLNYISVETEDENLQASVAEKKVESEKKL 748
            :....:::|.:|    ..|||..|   ...|.|      |.:|| |||.....:|.:......:
  Rat   483 DSMIRKFLEGNSMKLASLEREQHP---PHGEEL------YHTVE-EDETFSVDLANRPPVPVPR- 536

  Fly   749 PEAGNQPGPEKTTNELRINEPPYYQSK---EQNQQPKELKNQSKSLDEVDAAPLYQTDKFSQECS 810
            ||. :.|||    :.|..|||  |.||   |::|:
  Rat   537 PET-STPGP----HPLPDNEP--YISKVFAEKSQE------------------------------ 564

  Fly   811 QLLENQLGNDYVLQPSNVPVAQDDGNYLFQPSNRPVEEPLRLNRCTNRQPGYGTLKRSASDASAA 875
                 ::||.||   |:..:.::           |:..|.|     :|.|.      |..|..|.
  Rat   565 -----RVGNFYV---SSESIRKE-----------PLVRPWR-----DRPPS------SIYDPFAG 599

  Fly   876 SHTRSNADDELAEIMHDFKNNVLSIRDVEVLVERWK-HRNDVQQSFREKQDQIDQLRREYERIQ- 938
            ..|....  :|..:....|..::::.:..:..:.|: ::....:|||.:|:.:.:||....|.|
  Rat   600 MKTPGQR--QLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRRQR 662

  Fly   939 EQVKS----------------HLKRETPF------ERIKKFFLRSKTPGGNDSLLDETKSSIATS 981
            |:.||                ||..:..|      .|...|..|::...| |...|.| ||.|:|
  Rat   663 EKQKSGKHADLEITVPIRHSQHLPGKVEFGVYESGPRKSVFPARTELRRG-DWKTDST-SSTASS 725

  Fly   982 CSFKSAGGVSSSAGAGRPISSLSLQSVSSSSSSSGRLSTGSNCSGASLGDSGTHSDHEDRRFPHC 1046
            .|.:|              |:.||.|||                      ||...|:||...|..
  Rat   726 TSNRS--------------STRSLLSVS----------------------SGMEGDNEDNEVPEI 754

  Fly  1047 RMMDNYMVPPTP-----RPVFTPSSTPGDERHQIVFPS-----------PMSSCQRLNTP-TSPT 1094
            .....    |.|     .||.|.:.....||...|.|.           |:.:.:|..:| |..|
  Rat   755 TRSRG----PGPTQVDGAPVVTGTPVGILERPPRVPPRAASQSTACVQVPLEARRRHCSPGTGLT 815

  Fly  1095 GSEHYQMFPSNI-PVYGSQPLVGSQSSN---YLNTIM--EAKEQAETQHYQNQNGVTLQPIKLNE 1153
            ||:....||:.: .:..|:.|.|...:|   .:|:|:  .|.|...:....|.
  Rat   816 GSDTASSFPTLVTSLTSSKALCGRHLANIYSQINSILVYAAPELHSSVMASNP------------ 868

  Fly  1154 RSNIIYGKLTKSSSASGCSSFKPKQIPVP 1182
                  |.|..||||   ||.:...||.|
  Rat   869 ------GALPSSSSA---SSTQRSLIPPP 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stumps	NP_731923.2	DBB	423..562	CDD:291229	32/142 (23%)
Pik3ap1	XP_038965054.1	TIR_3	11..142	CDD:408351	24/140 (17%)
		DBB	181..319	CDD:405266	32/142 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352179
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JV2
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008315
OrthoInspector	1	1.000	-	-		oto97363
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16267
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6297
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.840