Protein Alignment stumps and Pik3ap1

DIOPT Version :10

• Sequence 1: NP_731923.2
• Gene: stumps / 41770
• FlyBaseID: FBgn0020299
• Length: 1220
• Species: Drosophila melanogaster
• Sequence 2: XP_063143395.1
• Gene: Pik3ap1 / 294048
• RGDID: 1307744
• Length: 849
• Species: Rattus norvegicus
• Alignment Length: 1049
• Identity: 227/1049 - (21%)
• Similarity: 373/1049 - (35%)
• Gaps: 311/1049 - (29%)

  Fly   236 SASGFLGSPGYNMDDILIITAKHSERAYLRATFLKNHFDKITKQRGRKPFNFLHIKIDDGPFSEE 300
            :|||:    |:.. ||||..:..:|.   ...:|::.|....:.|.:|...:.  .:.|..||.:
  Rat     2 AASGW----GWGC-DILIFYSPDAEE---WCQYLQDLFVSCRQVRSQKIQTYR--LVPDACFSSQ 56

  Fly   301 IAHKYQNTALQIVILCPALLALPHSFLMTQLSAIIR-----VEKVLAILLDVSEEKVKEMHKSAL 360
            ....:::....:|:|...|:   ..|:...|..:::     .::|:.:|..|...  .|..::..
  Rat    57 DLSVFRDARCVLVLLSAGLV---ECFVQPGLLPVLQRACHPPQRVVRLLCGVQPN--DEDFQAFF 116

  Fly   361 PSYYKWRRCVVRDNDQVQISNILGIATDILG------------RALCQRP-------PCQDSSGG 406
            |.:..|:.....|..:..::.:....::..|            |||   |       |.:.|.|
  Rat   117 PDWAHWQELTCDDEPETYLAAVRKAISEDSGCDSVTDTEPEDERAL---PFSKHTDLPLETSPG- 177

  Fly   407 GGGGLSRSFSSCTEGFTVLPKKVKLGQNKVVALLAEPLEKNDTLKLQVEKSGE---LIELRNFKC 468
                         ....|.|.:::.|....|.::.. .:.::.:..:||.|.|   .:.:.. ..
  Rat   178 -------------NLMVVQPDRIRCGAETTVYVIVR-CKLDEKVSTEVEFSPEDSPSVRMEG-TL 227

  Fly   469 RNPYTLQFNIPEACMEISTMIEIRIEKNNKSLGARPIKCESRLRELEQLLRIEDSPIEFMCHALG 533
            .|.||:....|:..   |..:.:::...:..:....|...:.:.|:..||....:|:||||.|..
  Rat   228 ENEYTVSVKAPDLS---SGNVSLKVYSGDLVVCETTISYYTDMEEIGNLLSSAANPVEFMCQAFK 289

  Fly   534 IGPVERDALDQHLLQCFQRNMPPN-FHLLSGPSERQPHFFTRLESSPEEYPTLLHFAARWGLNRL 597
            |.|...:.||:.|.:..:.|:|.: .||.......:....|  ....||.||||||||::||..|
  Rat   290 IVPYNTETLDKLLTESLKNNIPASGLHLFGINQLEEDDMMT--NQRDEELPTLLHFAAKYGLKNL 352

  Fly   598 CIQLMECPGGDTACGVRNCAGRTPAELAEQEGHHKLAQNIVSFAEFHEL---------------- 646
            ...|:.|||...|..|.|..|..|..:||:.|...|.|.|..:.|..::
  Rat   353 TALLLTCPGALQAYSVANKHGHYPNTIAEKHGFRDLRQFIDEYVETVDMLKSHIKEELMQGEEAD 417

  Fly   647 ---TTMYH-----YFKGVTPPG------ES----CPKPSANVVIE------AHPVKAGKTNKPPK 687
               .:|.|     ..|....||      ||    .|..:.::.:|      .:||.....::|.|
  Rat   418 DVYESMAHLSTDLLMKCSLNPGCDDELYESMAAFAPAATEDLYVEMLQASAGNPVSGESFSRPTK 482

  Fly   688 ELPTAEYMEMSS----GSERENTPEVRTKTETLAISNLNYISVETEDENLQASVAEKKVESEKKL 748
            :....:::|.:|    ..|||..|   ...|.|      |.:|| |||.....:|.:......:
  Rat   483 DSMIRKFLEGNSMKLASLEREQHP---PHGEEL------YHTVE-EDETFSVDLANRPPVPVPR- 536

  Fly   749 PEAGNQPGPEKTTNELRINEPPYYQSK---EQNQQPKELKNQSKSLDEVDAAPLYQTDKFSQECS 810
            ||. :.|||    :.|..|||  |.||   |::|:
  Rat   537 PET-STPGP----HPLPDNEP--YISKVFAEKSQE------------------------------ 564

  Fly   811 QLLENQLGNDYVLQPSNVPVAQDDGNYLFQPSNRPVEEPLRLNRCTNRQPGYGTLKRSASDASAA 875
                 ::||.||   |:..:.::           |:..|.|     :|.|.      |..|..|.
  Rat   565 -----RVGNFYV---SSESIRKE-----------PLVRPWR-----DRPPS------SIYDPFAG 599

  Fly   876 SHTRSNADDELAEIMHDFKNNVLSIRDVEVLVERWK-HRNDVQQSFREKQDQIDQLRREYERIQ- 938
            ..|....  :|..:....|..::::.:..:..:.|: ::....:|||.:|:.:.:||....|.|
  Rat   600 MKTPGQR--QLITLQEQVKLGIVNVDEAVLHFKEWQLNQKKRSESFRFQQENLKRLRDSITRRQR 662

  Fly   939 EQVKS----------------HLKRETPF------ERIKKFFLRSKTPGGNDSLLDETKSSIATS 981
            |:.||                ||..:..|      .|...|..|::...| |...|.| ||.|:|
  Rat   663 EKQKSGKHADLEITVPIRHSQHLPGKVEFGVYESGPRKSVFPARTELRRG-DWKTDST-SSTASS 725

  Fly   982 CSFKSAGGVSSSAGAGRPISSLSLQSVSSSSSSSGRLSTGSNCSGASLGDSGTHSDHEDRRFPHC 1046
            .|.:|              |:.||.|||                      ||...|:||...|.
  Rat   726 TSNRS--------------STRSLLSVS----------------------SGMEGDNEDNEVPE- 753

  Fly  1047 RMMDNYMVPPTPRPVFTPSSTPGD---ERHQIVFPSPMSSCQRLNTPTSPTGSEHYQMFPSNIPV 1108
                           .|.|..||.   :...:|..:|:...:|                |..:|
  Rat   754 ---------------ITRSRGPGPTQVDGAPVVTGTPVGILER----------------PPRVP- 786

  Fly  1109 YGSQPLVGSQSSNYLNTIMEAKEQAETQHYQNQNGVTLQPIKLNERSNIIYGKLTKSSSASGCSS 1173
                |...|||:..:...:||:.    :|.....|:|      ...||  .|.|..||||   ||
  Rat   787 ----PRAASQSTACVQVPLEARR----RHCSPGTGLT------GSASN--PGALPSSSSA---SS 832

  Fly  1174 FKPKQIPVP 1182
            .:...||.|
  Rat   833 TQRSLIPPP 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stumps	NP_731923.2	DBB	423..562	CDD:464205	32/142 (23%)
Pik3ap1	XP_063143395.1	None