DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7987 and wor

DIOPT Version :9

Sequence 1:	NP_650375.1	Gene:	CG7987 / 41768	FlyBaseID:	FBgn0038244	Length:	1283	Species:	Drosophila melanogaster
Sequence 2:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	570	Identity:	133/570 - (23%)
Similarity:	209/570 - (36%)	Gaps:	170/570 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 QLVASYPDT-VAQPAAPSRGRIS----RLKPKEESSQFIVISDKSVEDSRPYMEPEP-------- 311
            ::..::||. ..:..|.|..|:.    .|.|:||                 .|||||
  Fly    89 EIARAFPDVFTREEIAKSLARLGYGEFELPPEEE-----------------VMEPEPEPEQHLPL 136

  Fly   312 -----AQPVVTTSEFIAVEPPPQPNFPVLDHSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFEC 371
                 |.|.:     |..||..:..||:.:::                       |:.:.|..|.
  Fly   137 RYTRDASPTI-----IKAEPSDEEQFPLRNYN-----------------------NNLLKSIAEY 173

  Fly   372 NQCQEMFWDNSSLQEHQKTHQFEESNSEYDPAS-AEESGSESEADEQLYGEFYCNECGISFHRQD 435
            ..|.:|    .:::|  :..........|.|.: ..|....|....::..|        :.:.|:
  Fly   174 EDCMKM----QNIKE--EIPPIPSPQLFYPPPTPLAEPEDLSVTQRRVLSE--------NMNLQN 224

  Fly   436 LLR-----RH-AKMHCKPS-DQAAVGSNSDVTAGGDVELAKDSSG---HCCNTCGKSFPSALEML 490
            :.|     :| |..|..|. |......|.|:.     :|...||.   :.|..|.|.:.:...::
  Fly   225 VARALLSMQHMAPQHAPPPIDMEEDQENQDIN-----QLKIKSSNDLYYQCQQCNKCYATYAGLV 284

  Fly   491 AHAEIHARFPPFKCVLCGISFYE--EQAIKRHLHTRHPSELNANSCVLCGKE-CRDR-KALIKHA 551
            .|.:.||              ||  |..|.|       |:...:..::...| |.|: .|||:.|
  Fly   285 KHQQTHA--------------YESTEYKIIR-------SQPGGSGAIVDQTEFCTDQASALIQAA 328

  Fly   552 WDHSREKC--------HSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHS 608
            ...|.:..        :.|..|||::...:.|.:|...|         |..  .:|..:.
  Fly   329 NVASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFH---------CPS--AEGNQVK----- 377

  Fly   609 HSTTTPGKLFPCLECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKP 673
                   |:|.|..|.||:.|..:.::|:|.||  .|..|..|.|||:....|:.|.|.||||||
  Fly   378 -------KVFSCKNCDKTYVSLGALKMHIRTHT--LPCKCPICGKAFSRPWLLQGHIRTHTGEKP 433

  Fly   674 YACSVCPRAFNQRVVLREHIRSHHSGLDVARNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQR 738
            ::|..|.|||..|..||.|:::|.   ||.:  |.|..|::..:..:.|.:||  .|...|.:..
  Fly   434 FSCQHCNRAFADRSNLRAHMQTHS---DVKK--YSCPTCTKSFSRMSLLAKHL--QSGCQTEQSG 491

  Fly   739 QPVTGPRKYKRRRKLQPHEIAHMRAANKH----------VNGDEEEAIGE 778
            .| :|......:::||.|...:....|.|          .||:|||. ||
  Fly   492 GP-SGSGGGFDQQQLQQHLQVYEEGHNPHQLYYAGSVGSSNGEEEEG-GE 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7987	NP_650375.1	C2H2 Zn finger	142..162	CDD:275368
		C2H2 Zn finger	170..186	CDD:275368
		COG5048	326..734	CDD:227381	100/430 (23%)
		C2H2 Zn finger	343..363	CDD:275368	0/19 (0%)
		C2H2 Zn finger	371..391	CDD:275368	3/19 (16%)
		C2H2 Zn finger	424..444	CDD:275368	4/25 (16%)
		C2H2 Zn finger	476..496	CDD:275368	4/19 (21%)
		C2H2 Zn finger	504..523	CDD:275368	5/20 (25%)
		C2H2 Zn finger	534..554	CDD:275370	7/21 (33%)
		C2H2 Zn finger	562..582	CDD:275370	6/19 (32%)
		C2H2 Zn finger	589..609	CDD:275368	2/19 (11%)
		C2H2 Zn finger	620..640	CDD:275368	7/19 (37%)
		C2H2 Zn finger	648..668	CDD:275368	8/19 (42%)
		zf-H2C2_2	661..685	CDD:290200	14/23 (61%)
		C2H2 Zn finger	676..696	CDD:275368	9/19 (47%)
		C2H2 Zn finger	709..726	CDD:275371	3/16 (19%)
		Hph	921..>1017	CDD:290417
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	4/19 (21%)
		C2H2 Zn finger	317..334	CDD:275368	7/16 (44%)
		zf-C2H2	345..367	CDD:278523	6/21 (29%)
		C2H2 Zn finger	347..367	CDD:275368	6/19 (32%)
		PHA00732	379..>417	CDD:177300	16/39 (41%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		zf-C2H2_8	405..482	CDD:292531	33/83 (40%)
		zf-C2H2	406..428	CDD:278523	8/21 (38%)
		C2H2 Zn finger	408..428	CDD:275368	8/19 (42%)
		zf-H2C2_2	421..444	CDD:290200	13/22 (59%)
		zf-C2H2	434..456	CDD:278523	9/21 (43%)
		C2H2 Zn finger	436..456	CDD:275368	9/19 (47%)
		zf-H2C2_2	448..473	CDD:290200	9/29 (31%)
		C2H2 Zn finger	464..481	CDD:275368	3/16 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010