DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7987 and znf-782

DIOPT Version :9

Sequence 1:	NP_650375.1	Gene:	CG7987 / 41768	FlyBaseID:	FBgn0038244	Length:	1283	Species:	Drosophila melanogaster
Sequence 2:	NP_500033.1	Gene:	znf-782 / 190310	WormBaseID:	WBGene00021931	Length:	662	Species:	Caenorhabditis elegans

Alignment Length:	729	Identity:	175/729 - (24%)
Similarity:	268/729 - (36%)	Gaps:	160/729 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   381 NSSLQE--HQKTHQFEESNSEYDPASAEESGSESEADEQLYGEFYCNECGISFHRQDLLRRHAKM 443
            |::|.:  |.|..: ||...||:....||   |.|.||:|      .|...|.....|:.. ...
Worm    12 NTTLPDDIHMKDPE-EEEFEEYEDELLEE---EEEFDEEL------EELENSDSASSLVSA-GSP 65

  Fly   444 HCKPSDQAAVGSNSDVTAGGDVELAKDSSG------------HCCNTCGKSFP--SALEMLAHAE 494
            |...|...:.||:..:    .|:.....||            |.|..|||.|.  |.||  :|..
Worm    66 HGSSSSNGSHGSSPPL----QVQSPSQGSGSSGSPTGQPEKRHICTVCGKGFSYFSILE--SHKR 124

  Fly   495 IHARFPPFKCVLCGISFYEEQAIKRHLHTRHPSELNANSCVLCGKECRDRKALIKHAWD-HSREK 558
            .|....|:.|..|..:|.::..::.|..| |..| ....|..|.|..........|... |...:
Worm   125 SHTGEKPYNCHFCQKTFAQKATLQVHERT-HTGE-RPYKCRYCEKTFAQYGTKTVHEKSAHLGIR 187

  Fly   559 CHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNH-RHSHSTTTPGKLFPCLE 622
            .:.|.||.|...:.:.|..|..:|.||:..|:.|.:.|.....|..| :..|....  :...|:.
Worm   188 NYKCPKCDKLLSSPSALYTHKKTHGDKTFRCDFCPKTFALKNYLKLHVKQVHEQNE--RKHVCVY 250

  Fly   623 CGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRV 687
            |.|.|....|.|:|||.|||||||.|::|.||||..|.|:.|||.||||:||:|..|.|.|.|:.
Worm   251 CNKGFAYAGSLQVHVRTHTGERPYVCKFCPKAFASQGNLQSHERTHTGERPYSCQFCQRTFIQKS 315

  Fly   688 VLREHIRSH----HSG---------LDVARN--------TYHCTVCSEDLASSNDLIQHLIQHSD 731
            .|..|..:|    ||.         |.||.:        .|.||.|::....::.|..|:.:|
Worm   316 QLTAHESTHLTQKHSVNPDSTTADILPVAGSVTDHQMVGNYECTFCNKKYPYASSLYIHMRKH-- 378

  Fly   732 SNTAKQRQPVTGPRK-YKRRRKLQPHEIAHMRAANKHVNGDEE-----EAIGEGDAEECASDIDF 790
              |.|......|..| |.::..|..|:.......|:....|.:     :..|:...:..|..|
Worm   379 --TEKSAYSCDGCGKPYSQKISLNIHQDQCEAFKNRLKTTDSQFSHNCDGCGKSFVQRIALQI-- 439

  Fly   791 CDFDVENVDDIFDMAESPKKEKRKRGSAATKADAKPVTNGKAAKPAQDKGKAKPRYDSTSSQQSD 855
                  :||                                :.:|.::..:.|.......:|.||
Worm   440 ------HVD--------------------------------SCEPHKNLARLKLSQQQNQNQNSD 466

  Fly   856 RLWEEKFLHDSQVALFQI-DSLVVVNDTHLQ---PASSAVSANIPNTRGGSKQQGKVQAKSVEGA 916
               .|.   |:::.:..: :..:.:..||.|   |.:.......||..|           |:.|
Worm   467 ---SES---DTEMKICPLPNPPLTLAPTHQQIPPPVNIYAQQPPPNPLG-----------SILG- 513

  Fly   917 ENLNSSATTSDTTFSASTSTASTRSRKRAATTKTASKAP------PASNSRPRMI--HT------ 967
               |:|.|.....|...:.::::.|...|....|..:.|      |.:.|:|..:  |.
Worm   514 ---NTSLTPQTLNFGLPSLSSASFSSLNAHAPFTPVELPNSADFGPLTASKPHAVPFHPSEMCLS 575

  Fly   968 --EKAKVTKGVGG-DSTSSSAKKTRSKTYISRTESHNLSLDKSRSSASNMVDDYEIIS--PATHP 1027
              .|...:..:.| .|.|:|...|:....:..|...|..|::      |::.....:|  .||..
Worm   576 AFRKVPESSSISGLGSLSTSILSTQLLLQLQHTPDFNYLLNQ------NLLSSLAGLSGLSATLG 634

  Fly  1028 PNQISSSPLHIKQE 1041
            |...:::|....|:
Worm   635 PQLQATTPTSANQQ 648

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7987	NP_650375.1	C2H2 Zn finger	142..162	CDD:275368
		C2H2 Zn finger	170..186	CDD:275368
		COG5048	326..734	CDD:227381	117/391 (30%)
		C2H2 Zn finger	343..363	CDD:275368
		C2H2 Zn finger	371..391	CDD:275368	4/11 (36%)
		C2H2 Zn finger	424..444	CDD:275368	3/19 (16%)
		C2H2 Zn finger	476..496	CDD:275368	9/21 (43%)
		C2H2 Zn finger	504..523	CDD:275368	4/18 (22%)
		C2H2 Zn finger	534..554	CDD:275370	4/20 (20%)
		C2H2 Zn finger	562..582	CDD:275370	6/19 (32%)
		C2H2 Zn finger	589..609	CDD:275368	5/20 (25%)
		C2H2 Zn finger	620..640	CDD:275368	9/19 (47%)
		C2H2 Zn finger	648..668	CDD:275368	11/19 (58%)
		zf-H2C2_2	661..685	CDD:290200	14/23 (61%)
		C2H2 Zn finger	676..696	CDD:275368	7/19 (37%)
		C2H2 Zn finger	709..726	CDD:275371	4/16 (25%)
		Hph	921..>1017	CDD:290417	21/112 (19%)
znf-782	NP_500033.1	C2H2 Zn finger	106..126	CDD:275368	9/21 (43%)
		zf-H2C2_2	119..143	CDD:290200	8/25 (32%)
		C2H2 Zn finger	134..154	CDD:275368	5/20 (25%)
		zf-H2C2_2	147..171	CDD:290200	7/25 (28%)
		C2H2 Zn finger	162..180	CDD:275368	4/17 (24%)
		COG5048	<187..404	CDD:227381	75/222 (34%)
		C2H2 Zn finger	191..211	CDD:275370	6/19 (32%)
		C2H2 Zn finger	218..239	CDD:275368	5/20 (25%)
		C2H2 Zn finger	248..268	CDD:275368	9/19 (47%)
		zf-H2C2_2	260..285	CDD:290200	17/24 (71%)
		C2H2 Zn finger	276..296	CDD:275368	11/19 (58%)
		zf-H2C2_2	288..313	CDD:290200	14/24 (58%)
		C2H2 Zn finger	304..324	CDD:275368	7/19 (37%)
		C2H2 Zn finger	386..403	CDD:275368	4/16 (25%)
		C2H2 Zn finger	424..441	CDD:275368	3/24 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000