Protein Alignment CG7987 and ZNF792

DIOPT Version :10

• Sequence 1: NP_650375.1
• Gene: CG7987 / 41768
• FlyBaseID: FBgn0038244
• Length: 1283
• Species: Drosophila melanogaster
• Sequence 2: NP_787068.3
• Gene: ZNF792 / 126375
• HGNCID: 24751
• Length: 632
• Species: Homo sapiens
• Alignment Length: 750
• Identity: 183/750 - (24%)
• Similarity: 269/750 - (35%)
• Gaps: 217/750 - (28%)

  Fly    43 VAAENLIFMARDGQL---SEIMAANEAGRTVLV--TADGTTV----AYAESFDDDAQVVTEEVIT 98
            |..||...:|..|.:   |.|::..|.|:...|  :.|.|:.    ||.....|..
Human    42 VMLENFALIASLGLISFRSHIVSQLEMGKEPWVPDSVDMTSAMARGAYGRPGSDFC--------- 97

  Fly    99 DDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPY---PCDFCSRRFRKKATLNNHML 160
                  .|.|..::.:|.    :.|.|.:..::.....|.|.   |||.|..|.:....|..|..
Human    98 ------HGTEGKDLPSEH----NVSVEGVAQDRSPEATLCPQKTCPCDICGLRLKDILHLAEHQT 152

  Fly   161 AHQNDRPHLCK--LCGARFSRRAELISHFKAHAEAQDAADAEAAAAAADSSSAIKFEHQTQRQLD 223
            .|...:|.:|:  :.|:.||  |.|
Human   153 THPRQKPFVCEAYVKGSEFS--ANL---------------------------------------- 175

  Fly   224 DHYYEQEWPLFQHQQEQENAQQNVHQQHQIVEEGGIQLVASYPDTVAQPAAPSRGRISRLKPKEE 288
                           .::..|||||...: .|||....|.:..|..:...:..|
Human   176 ---------------PRKQVQQNVHNPIR-TEEGQASPVKTCRDHTSDQLSTCR----------- 213

  Fly   289 SSQFIVISDKSVEDSRPYMEPEPAQPVVTTSEFIAVEPPPQPNFP------------VLDHSKPF 341
                                 |..:..|.|:.|:..|..|....|            .|.|:|
Human   214 ---------------------EGGKDFVATAGFLQCEVTPSDGEPHEATEGVVDFHIALRHNK-- 255

  Fly   342 VCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQEHQKTHQFEESNSEYDPASAE 406
             |.:.|.||..:..||.|.:.|..:.|:||::|...|...:.|.:|||.|.
Human   256 -CCESGDAFNNKSTLVQHQRIHSRERPYECSKCGIFFTYAADLTQHQKVHN-------------- 305

  Fly   407 ESGSESEADEQLYGEFY-CNECGISFHRQDLLRRHAKMHCKPSDQAAVGSNSDVTAGGDVELAKD 470
                        .|:.| |.|||..|.:...|.:|.::|                        ..
Human   306 ------------RGKPYECCECGKFFSQHSSLVKHRRVH------------------------TG 334

  Fly   471 SSGHCCNTCGKSFPSALEMLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPSELNANSCV 535
            .|.|.|..|||.|..:..::.|..:|....|::|..|| .|:.:::...| |.|..:..:|:.|.
Human   335 ESPHVCGDCGKFFSRSSNLIQHKRVHTGEKPYECSDCG-KFFSQRSNLIH-HKRVHTGRSAHECS 397

  Fly   536 LCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHR-DKSVVCEVCQEEFPDG 599
            .|||......:||||...|:.|:.:.|::|||.|.:.|.|.:|...|. ::...|..|.:.|...
Human   398 ECGKSFNCNSSLIKHWRVHTGERPYKCNECGKFFSHIASLIQHQIVHTGERPHGCGECGKAFSRS 462

  Fly   600 RTLSNHRHSHSTTTPGKLFPCLECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKH 664
            ..|..|:..|:...|   :.|.||||.|...||...|.|:|||||||.|..|.|.|....:|..|
Human   463 SDLMKHQRVHTGERP---YECNECGKLFSQSSSLNSHRRLHTGERPYQCSECGKFFNQSSSLNNH 524

  Fly   665 ERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARNTYHCTVCSEDLASSNDLIQH---- 725
            .|:||||:||.||.|.:.|.||..||:|::.|...     ..|.|:.|.:.......||:|
Human   525 RRLHTGERPYECSECGKTFRQRSNLRQHLKVHKPD-----RPYECSECGKAFNQRPTLIRHQKIH 584

  Fly   726 ------------LIQHSDSNTAKQRQPVTGPRKYK 748
                        ..||:...:::.| |..|...||
Human   585 IRERSMENVLLPCSQHTPEISSENR-PYQGAVNYK 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7987	NP_650375.1	C2H2 Zn finger	142..162	CDD:275368	6/19 (32%)
		C2H2 Zn finger	170..186	CDD:275368	6/17 (35%)
		COG5048	326..734	CDD:227381	125/437 (29%)
		C2H2 Zn finger	343..363	CDD:275368	7/19 (37%)
		C2H2 Zn finger	371..391	CDD:275368	7/19 (37%)
		C2H2 Zn finger	424..444	CDD:275368	7/19 (37%)
		zf-C2H2_8	427..522	CDD:464935	21/94 (22%)
		C2H2 Zn finger	476..496	CDD:275368	6/19 (32%)
		C2H2 Zn finger	504..523	CDD:275368	5/18 (28%)
		C2H2 Zn finger	534..554	CDD:275370	8/19 (42%)
		C2H2 Zn finger	562..582	CDD:275370	8/19 (42%)
		C2H2 Zn finger	589..609	CDD:275368	5/19 (26%)
		C2H2 Zn finger	620..640	CDD:275368	10/19 (53%)
		C2H2 Zn finger	648..668	CDD:275368	7/19 (37%)
		zf-H2C2_2	661..685	CDD:463886	13/23 (57%)
		C2H2 Zn finger	676..696	CDD:275368	9/19 (47%)
		C2H2 Zn finger	709..726	CDD:275371	5/32 (16%)
ZNF792	NP_787068.3	KRAB	14..74	CDD:214630	9/31 (29%)
		C2H2 Zn finger	256..276	CDD:275368	7/19 (37%)
		C2H2 Zn finger	284..304	CDD:275368	7/19 (37%)
		C2H2 Zn finger	312..332	CDD:275368	7/19 (37%)
		C2H2 Zn finger	340..360	CDD:275368	6/19 (32%)
		COG5048	<348..592	CDD:227381	83/253 (33%)
		C2H2 Zn finger	368..388	CDD:275368	7/21 (33%)
		C2H2 Zn finger	396..416	CDD:275368	8/19 (42%)
		C2H2 Zn finger	424..444	CDD:275368	8/19 (42%)
		C2H2 Zn finger	452..472	CDD:275368	5/19 (26%)
		C2H2 Zn finger	480..500	CDD:275368	10/19 (53%)
		C2H2 Zn finger	508..528	CDD:275368	7/19 (37%)
		C2H2 Zn finger	536..556	CDD:275368	9/19 (47%)
		C2H2 Zn finger	564..584	CDD:275368	5/19 (26%)