Protein Alignment Pde6 and pde4cb

DIOPT Version :9

• Sequence 1: NP_001262566.1
• Gene: Pde6 / 41760
• FlyBaseID: FBgn0038237
• Length: 1124
• Species: Drosophila melanogaster
• Sequence 2: XP_021335380.1
• Gene: pde4cb / 571344
• ZFINID: ZDB-GENE-030131-4075
• Length: 721
• Species: Danio rerio
• Alignment Length: 664
• Identity: 158/664 - (23%)
• Similarity: 255/664 - (38%)
• Gaps: 170/664 - (25%)

  Fly   437 TKIMTEARELLKCERCSVFLVDLDCCEASHLEKIIEKPNQPATR-AIKSADSFEEKKMRNRFTVL 500
            |.:..||.:.|..|.    |.:||.| ...||.:       .|| ::....|.:.|:|.||
Zfish   177 TNLSDEAYQKLTVET----LEELDWC-LDQLETL-------QTRHSVSEMASNKFKRMLNR---- 225

  Fly   501 FELGGEYQAANVSRPSVSELSSSTLA--QIAQFVATTGQTVNICDVIEWVRDHNQIRAEDEIDST 563
                           .:::||.::.:  |:::|:|:|                 .::.:.:::..
Zfish   226 ---------------ELTQLSETSRSGNQVSEFIAST-----------------ILQKQYDVELL 258

  Fly   564 QAILCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKLMAKQ 628
            .| .|    ..:||...::|:.......|......:....|.:       ||| :|:   |:||:
Zfish   259 SA-AC----KEEKKRRPMSQISGVRKLSPSPSLPPTCIPRFGV-------NTQ-HES---LLAKE 307

  Fly   629 KVALECLSYHATASQDQTEKLTQDVIAEAESYNLYSFTFTDFELVDDDTCRAVLRMFMQCNLVSQ 693
               ||.|           ::...|:...||.......|...:.:            |.:.:|:..
Zfish   308 ---LEDL-----------DRWGIDIFKIAEYSGNRPLTVMMYTI------------FQERDLLKT 346

  Fly   694 FQIPYDVLCRWVLSVRKNYR-PVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLC 757
            |:||.|....:::::..:|. .|.|||..||.:|.|:...:|.|..:|...|||||:..|.|...
Zfish   347 FKIPSDTFLTFLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEDVFTDLEIMAALFASAI 411

  Fly   758 HDLDHRGTNNAFQTKTESPLAILYT-TSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTV 821
            ||:||.|..|.|...|.|.||::|. .|.:|:||......:|..|..:||..||.:..:|:.:..
Zfish   412 HDVDHPGVTNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFCNLSKKQRQSLRQMT 476

  Fly   822 ESAILSTDLAMYFKKRNAFLELVENGEFDWQG-------EEKKDLLCGMMMTACDVSAIAKPWEV 879
            ...:|:||::.:.........:||..:...||       .::..:|..|:..| |:|...||.|:
Zfish   477 IDMVLATDMSKHMNFLADLKTMVETKKVTSQGVLLLDNYSDRIQVLQNMVHCA-DLSNPTKPLEL 540

  Fly   880 QHKVAKLVADEFFDQGDLEKLQ-LNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCD-TFP 942
            ..|....:..|||.|||.|:.: ::..|  |.|:... .:...||||||.|..||:....| ..|
Zfish   541 YRKWTDRIMVEFFSQGDRERDKGIDVSP--MCDKHTA-SMENTQVGFIDYIIHPLWETWADLVHP 602

  Fly   943 WITPLYEGTLENRRNWQDLAEKVEMGLTWIDHDTIDKPVEEFAACADEEIKDIEFTVTTLNCNQQ 1007
            ....:.: |||:.|.|                                               .|
Zfish   603 DAQDILD-TLEDNREW-----------------------------------------------YQ 619

  Fly  1008 SQHGSEDSHTPEHQRSGSRLSMKKTGALGKAVRSKLSKTLYNSMDGSKPKTSLKLLESHVSEDMD 1072
            |......|.|||.|.|      :.||..|.|......:......||     .|:..|.|.  |::
Zfish   620 SMIPRSPSPTPEEQDS------RPTGVTGSAGEKFQFELTLEEEDG-----ELETEEEHT--DIE 671

  Fly  1073 -DKSPTSPSQPQAS 1085
             .::.|.|..||.|
Zfish   672 RSRTMTDPEHPQTS 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde6	NP_001262566.1	GAF	247..406	CDD:214500
		GAF	431..619	CDD:214500	34/184 (18%)
		PDEase_I	717..950	CDD:278654	77/242 (32%)
pde4cb	XP_021335380.1	PDEase_I	371..608	CDD:306695	77/240 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3689
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820