Protein Alignment Pde6 and pde3a

DIOPT Version :9

• Sequence 1: NP_001262566.1
• Gene: Pde6 / 41760
• FlyBaseID: FBgn0038237
• Length: 1124
• Species: Drosophila melanogaster
• Sequence 2: XP_009298269.1
• Gene: pde3a / 567051
• ZFINID: ZDB-GENE-041210-23
• Length: 1124
• Species: Danio rerio
• Alignment Length: 533
• Identity: 123/533 - (23%)
• Similarity: 202/533 - (37%)
• Gaps: 139/533 - (26%)

  Fly   664 SFTFTDFELVD--DDTCRAVL-----RMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWR 721
            ::.|..|.||:  :..|..:|     |:|:...|...|:||......:..::...||.:.|||..
Zfish   628 NWNFPIFSLVEKTNGRCGCILSQMSYRLFVDTGLFETFKIPVREFMNYFHALENGYRDIPYHNRI 692

  Fly   722 HALNVAQTMFAM----------LKT------------GKMERFMT------------------DL 746
            ||.:|...::.:          |:|            |:|:..|:                  .|
Zfish   693 HATDVLHAVWYLTTQPVPGLPTLRTLGSSDSDSGLAHGRMKYLMSRTNAVEEEGYGCLSGLIPAL 757

  Fly   747 EILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYT-TSTMEHHHFDQCVMILNSEGN-NIFQAL 809
            |::.|.||...||.||.|..|||...|.:|.|:||. .|.:|:||......:..|... |...:|
Zfish   758 ELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAASAWNLFMSRPEYNFLASL 822

  Fly   810 SPEDYRSVMKTVESAILSTDLAMYFKKRNAF-LELVENG--EFDWQGEEKKDLLCGMMMTACDVS 871
            ...:::.....|..|||:|||..:|.....| .::.::|  ..||..|..:.|:|.|.:...|::
Zfish   823 DHMEFKRFRFLVIEAILATDLKKHFDFLAEFNAKVGDDGCSGIDWTNENDRLLVCQMCIKLADIN 887

  Fly   872 AIAKPWEVQHKVAKLVADEFFDQGDLE-KLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYR 935
            ...|..::..:..:.:.:||::|||.| .|.|...|  .|||. ..:|.|:|..||..|..|
Zfish   888 GPLKCKDLHLQWTEGIVNEFYEQGDEESSLGLPISP--FMDRS-APQLAKLQESFITHIVGP--- 946

  Fly   936 VLCDTFP--------WITPLYEGTLENRRNWQDLAEKVEMGLTWIDHDTIDKPVEEFAACADEEI 992
             ||.::.        |:.||.:                       |.|.::...||    .||:.
Zfish   947 -LCSSYDSAALMPGRWVHPLPK-----------------------DGDEVEDESEE----EDEDT 983

  Fly   993 KDIEFTVTTLNCNQQSQHGSEDSHTPEHQRSGSRLSMKKTGALGKAVRSKLSKTLY--------- 1048
            .:.|               .||:.|      .|.||.|......:.|..::|..|.
Zfish   984 AEEE---------------EEDAST------SSELSQKPAPKKRRKVFCQISHHLLENHEMWKKV 1027

  Fly  1049 -----NSMDGSKPKTSLKLL-ESHVSEDMDDKSPTSPSQP---QASGSMGRMSA-----SSSTSS 1099
                 .|....:..|.|... |..::.|.:::.|.|..:|   |..||......     :..|..
Zfish  1028 IAEESQSQTEGEESTCLSTTPEPILAIDEEEEEPGSKEEPTDDQGEGSTEEEEGPVPEDTHETQE 1092

  Fly  1100 AGGQMVDKSKKRS 1112
            ..|:.|:::.:::
Zfish  1093 PDGETVEEADEKN 1105

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde6	NP_001262566.1	GAF	247..406	CDD:214500
		GAF	431..619	CDD:214500
		PDEase_I	717..950	CDD:278654	78/286 (27%)
pde3a	XP_009298269.1	PDEase_I	688..947	CDD:278654	73/265 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920