Protein Alignment Pde6 and pde3b

DIOPT Version :9

• Sequence 1: NP_001262566.1
• Gene: Pde6 / 41760
• FlyBaseID: FBgn0038237
• Length: 1124
• Species: Drosophila melanogaster
• Sequence 2: XP_691883.4
• Gene: pde3b / 563432
• ZFINID: ZDB-GENE-160728-20
• Length: 1103
• Species: Danio rerio
• Alignment Length: 488
• Identity: 121/488 - (24%)
• Similarity: 188/488 - (38%)
• Gaps: 117/488 - (23%)

  Fly   626 AKQKVALECLSYHATASQDQT-------EKLTQD-VIAEAESY--NLYSFTFTDFELVD---DDT 677
            |.:||..:......|:|.:|:       |:...| ::.|.|..  .:.::.|..|||:|   ..|
Zfish   613 AGEKVNSQPEEEEQTSSTEQSSLDPEGDEEFRLDLMLVEHEELMEKINTWNFQIFELMDLTGGKT 677

  Fly   678 CR----AVLRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAM----- 733
            .|    ....:|....|...|:||......:..::...||.:.|||..||.:|...::.:
Zfish   678 GRILSYVAYTLFQDTGLFEIFKIPVREFMTYFCALENGYRDIPYHNRVHATDVLHAVWYLTTQPI 742

  Fly   734 ----------------------------LKTGKMERFMTD-----------LEILGLLVACLCHD 759
                                        ..|.|...|..|           ||::.|.||...||
Zfish   743 PGFQQIHNEHVTGSDTDSDSGISPGRVAYATSKSSSFQDDSYGCLAWNVPALELMALYVAAAMHD 807

  Fly   760 LDHRGTNNAFQTKTESPLAILYT-TSTMEHHHFDQC-VMILNSEGNNIFQALSPEDYRSVMKTVE 822
            .||.|..|||...|.:|.|:||. .|.:|:||.... .:.|:....|....|...:::.....|.
Zfish   808 YDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWSLFLSRPEFNFLCNLDHVEFKRFRFLVI 872

  Fly   823 SAILSTDLAMYF---KKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVA 884
            .|||:|||..:|   .:.|:.:..|.:...||..|..:.|:|.:.:...|::..||...:..|..
Zfish   873 EAILATDLKKHFDFLAEFNSKVNDVNSPGIDWTNENDRLLVCQVCIKLADINGPAKDRSLHLKWT 937

  Fly   885 KLVADEFFDQGDLE-KLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFP------ 942
            :.:.:||::|||.| .|.|...|  .|||. ..:|.|:|..||..|..|    ||:::.
Zfish   938 EGIVNEFYEQGDEEGTLGLPISP--FMDRS-APQLAKLQESFITHIVGP----LCNSYDAAGLLP 995

  Fly   943 --WITPLYEG------TLENRRNWQDLAEKVE--------------MGLTWIDHDTIDKPVEEFA 985
              ||..  ||      |.:|....::|.|.:|              |.....:|....|.:||
Zfish   996 GYWIDE--EGSDDEEETEDNETEDEELDEDLEPKRRKRRRRLFCNIMQHLTENHKVWKKTIEE-- 1056

  Fly   986 ACADEEIKDIEFTVTTLNCNQQSQHGSEDSHTP 1018
               :|:.|::|        .||.|...:.|..|
Zfish  1057 ---EEKAKELE--------TQQKQQQQQQSEGP 1078

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde6	NP_001262566.1	GAF	247..406	CDD:214500
		GAF	431..619	CDD:214500
		PDEase_I	717..950	CDD:278654	77/290 (27%)
pde3b	XP_691883.4	PDEase_I	721..995	CDD:278654	75/280 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920