Sequence 1: | NP_001262566.1 | Gene: | Pde6 / 41760 | FlyBaseID: | FBgn0038237 | Length: | 1124 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_002590.1 | Gene: | PDE2A / 5138 | HGNCID: | 8777 | Length: | 941 | Species: | Homo sapiens |
Alignment Length: | 870 | Identity: | 265/870 - (30%) |
---|---|---|---|
Similarity: | 423/870 - (48%) | Gaps: | 119/870 - (13%) |
- Green bases have known domain annotations that are detailed below.
Fly 158 EKW---LTERAPPEALSRLQEFIENRKPHKRPSVTSDLFQQWMAASPTVQQKSPRSLSNSSASSL 219
Fly 220 PECRRHLMDLDEGELFMELIRDVANELDIDVLCHKILVNVGLLTHADRGSLFLAKGTPTNKYLVA 284
Fly 285 KLFDVTQKTALKDAVTRASAEEIIIPFGIGIAGMVAQTKQMINIKE-AYKDARFNCEIDLKTGYK 348
Fly 349 TNAILCMPICNYEGD-IIGVAQIINKTNGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEY 412
Fly 413 RRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEASHLEKIIEKPNQP 477
Fly 478 ATRAIKSADSFEEKKMRNRFTVLFELGGEYQAANVSRPSVSELSSSTLAQIAQFVATTGQTVNIC 542
Fly 543 DV------IEWVRDHNQIRAEDEIDSTQAILCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIF 601
Fly 602 EAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQDVI--AEAESYNLYS 664
Fly 665 FTFTDFELVDDDTCRAVLRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQT 729
Fly 730 MFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTT--STMEHHHFD 792
Fly 793 QCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKK 857
Fly 858 DLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQ 922
Fly 923 VGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLAEKVEM-GLTWIDHDTIDKPVEEFAA 986
Fly 987 CADEEIKDIEFTVTTLN--CNQQSQ 1009 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Pde6 | NP_001262566.1 | GAF | 247..406 | CDD:214500 | 36/160 (23%) |
GAF | 431..619 | CDD:214500 | 59/193 (31%) | ||
PDEase_I | 717..950 | CDD:278654 | 97/234 (41%) | ||
PDE2A | NP_002590.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 16..42 | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 196..221 | 6/29 (21%) | |||
GAF | 241..387 | CDD:214500 | 37/163 (23%) | ||
GAF | 409..558 | CDD:214500 | 60/196 (31%) | ||
PDEase_I | 655..885 | CDD:306695 | 95/232 (41%) | ||
Substrate binding | 656..660 | 3/3 (100%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3689 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D114875at33208 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.820 |