Protein Alignment Pde6 and Pde3a

DIOPT Version :9

• Sequence 1: NP_001262566.1
• Gene: Pde6 / 41760
• FlyBaseID: FBgn0038237
• Length: 1124
• Species: Drosophila melanogaster
• Sequence 2: NP_059033.1
• Gene: Pde3a / 50678
• RGDID: 61942
• Length: 1141
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 116/511 - (22%)
• Similarity: 197/511 - (38%)
• Gaps: 126/511 - (24%)

  Fly   662 LYSFTFTDFELVDD--DTCRAVL-----RMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHN 719
            |.::.|..|:||::  ..|..:|     |:|....|...|:||......:..::...||.:.|||
  Rat   689 LNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFEAFKIPVREFMNYFHALEIGYRDIPYHN 753

  Fly   720 WRHALNVAQTMFAML--------------------------------------------KTGKME 740
            ..||.:|...::.:.                                            |.|.:.
  Rat   754 RIHATDVLHAVWYLTTQPIPGLPSVIGDHGSASDSDSDSGFTHGHMGYVFSKAYHVPDDKYGCLS 818

  Fly   741 RFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYT-TSTMEHHHFDQCVMILNSEGN- 803
            ..:..||::.|.||...||.||.|..|||...|.:|.|:||. .|.:|:||......:..|...
  Rat   819 GNIPALELMALYVAAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEY 883

  Fly   804 NIFQALSPEDYRSVMKTVESAILSTDLAMYF---KKRNAFLELVENGEFDWQGEEKKDLLCGMMM 865
            |....|...:::.....|..|||:|||..:|   .|.||  ::.::...||..|..:.|:|.|.:
  Rat   884 NFLVNLDHVEFKHFRFLVIEAILATDLKKHFDFVAKFNA--KVNDDVGIDWTNENDRLLVCQMCI 946

  Fly   866 TACDVSAIAKPWEVQHKVAKLVADEFFDQGDLE-KLQLNTQPVAMMDRERKDELPKMQVGFIDVI 929
            ...|::..||..::..:..:.:|.||::|||.| .|.|...|  .|||. ..:|..:|..||..|
  Rat   947 KLADINGPAKCKDLHLRWTEGIASEFYEQGDEEASLGLPISP--FMDRS-APQLANLQESFISHI 1008

  Fly   930 CLPLYRVLCDTFPWITPLYEGTLENRRNWQDLAEKVEMGLTWIDHDTIDKPVEEFAACADEEIKD 994
            ..|    ||.::.     ..|.:..:  |.|.::         |....|.|.||     :||
  Rat  1009 VGP----LCHSYD-----SAGLMPGK--WVDDSD---------DSGDTDDPEEE-----EEE--- 1045

  Fly   995 IEFTVTTLNCNQQSQHGSEDSHTPEHQRSGSRLSMKKTGALGKAVRSKLSKTLYNSMDGSKPKTS 1059
                       .::.|..|   |.|:..:..:.|.|:             :.:|..:       :
  Rat  1046 -----------AETPHEEE---TCENSEAPRKKSFKR-------------RRIYCQI-------T 1076

  Fly  1060 LKLLESHV--SEDMDDKSPTSPSQPQASGSMGRMSASSSTSSAGGQMVDKSKKRSK 1113
            ..||::|:  .:.::::...|.::.||........:|....:...:..:|.|.|::
  Rat  1077 QHLLQNHMMWKKVIEEEQCLSGTENQAPDQAPLQHSSEQIQAIKEEEEEKGKPRAE 1132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde6	NP_001262566.1	GAF	247..406	CDD:214500
		GAF	431..619	CDD:214500
		PDEase_I	717..950	CDD:278654	74/282 (26%)
Pde3a	NP_059033.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..111
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..309
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	433..479
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	504..643
		PDEase_I	751..1012	CDD:278654	72/269 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1024..1062		13/70 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1098..1141		6/35 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920