Protein Alignment Pde6 and pde-4

DIOPT Version :9

• Sequence 1: NP_001262566.1
• Gene: Pde6 / 41760
• FlyBaseID: FBgn0038237
• Length: 1124
• Species: Drosophila melanogaster
• Sequence 2: NP_871945.1
• Gene: pde-4 / 174235
• WormBaseID: WBGene00020114
• Length: 674
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 134/558 - (24%)
• Similarity: 215/558 - (38%)
• Gaps: 118/558 - (21%)

  Fly   456 LVDLDCCEASHLEKIIEKPNQPATRAIKSADSFEEKKMRNRFTVLFELGGEYQAANVSRPSVSEL 520
            |.:||.| ...||.|      ...|::....|.:.:||.|:     ||            |....
 Worm   215 LEELDWC-LDQLETI------QTHRSVSEMASSKFRKMLNK-----EL------------SHFAE 255

  Fly   521 SSSTLAQIAQFVATTGQTVNICDVIEWVRDHNQIRAE--DEID--STQAILCMPIMN-----AQK 576
            ||.:..|:::|:.||        .::...|...|..|  .|:.  ||...:.:.|:.     |..
 Worm   256 SSKSGTQVSKFLITT--------YMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMN 312

  Fly   577 KVIGVAQLINKANGVPFTDSDASIFEAFAIFCG--LGIHNTQMYENACKLMAKQKVALECLSYHA 639
            |:.||.:|...::       |..:.| :.:.|.  :.:|
 Worm   313 KISGVRKLRAPSH-------DGHVPE-YGVNCAREIAVH-------------------------- 343

  Fly   640 TASQDQTEKLTQDVIAEAESYNLYSFTFTDFELVDDDTCRAVLRMFMQCNLVSQFQIPYDVLCRW 704
               ..:.:....||....|....:|.|...|.|:            .|.||...|:|....|..:
 Worm   344 ---MQRLDDWGPDVFKIDELSKNHSLTVVTFSLL------------RQRNLFKTFEIHQSTLVTY 393

  Fly   705 VLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAF 769
            :|::..:||...|||:.||.:|||:|..:|.:..:....||||:|..:.|...||:||.|..|.:
 Worm   394 LLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQY 458

  Fly   770 QTKTESPLAILYT-TSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMY 833
            ...:.:.|||:|. .|.:|.||......:|.....:....||.:......|.|...:|:||::.:
 Worm   459 LINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKH 523

  Fly   834 FKKRNAFLELVENGEFDWQG-------EEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEF 891
            .........:||..:.....       .:|..:|..|:..| |:|...||.|:..:..:.:.:|:
 Worm   524 MSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLA-DLSNPTKPIELYQQWNQRIMEEY 587

  Fly   892 FDQGDLEK-LQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENR 955
            :.|||.|| |.|...|  |.||... .:.|.||||||.|..|||..      |...:|...
 Worm   588 WRQGDKEKELGLEISP--MCDRGNV-TIEKSQVGFIDYIVHPLYET------WADLVYPDA---- 639

  Fly   956 RNWQDLAEKVEMGLTWIDHDTIDKPVEEFAACADEEIK 993
               |::.:::|....|......::|........|:|.|
 Worm   640 ---QNILDQLEENREWYQSRIPEEPDTARTVTEDDEHK 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde6	NP_001262566.1	GAF	247..406	CDD:214500
		GAF	431..619	CDD:214500	37/173 (21%)
		PDEase_I	717..950	CDD:278654	74/241 (31%)
pde-4	NP_871945.1	PDEase_I	406..647	CDD:278654	75/257 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920