Protein Alignment Pde6 and pde3a

DIOPT Version :9

• Sequence 1: NP_001262566.1
• Gene: Pde6 / 41760
• FlyBaseID: FBgn0038237
• Length: 1124
• Species: Drosophila melanogaster
• Sequence 2: XP_031753954.1
• Gene: pde3a / 101730602
• XenbaseID: XB-GENE-6033578
• Length: 1022
• Species: Xenopus tropicalis
• Alignment Length: 669
• Identity: 151/669 - (22%)
• Similarity: 238/669 - (35%)
• Gaps: 205/669 - (30%)

  Fly   513 SRPSVSE-LSSSTLAQIAQFVATTGQTVNICDVIEWVRD-----HNQIRAED------EIDSTQA 565
            |.|.:.| ...|||.     .|:.|::.:..:..:...|     |:|.|.:|      :.|||..
 Frog   445 SAPEIPEPFPGSTLV-----CASCGRSYSPVNPSDGALDPGEVPHSQNRTDDPTHTTSDYDSTHE 504

  Fly   566 ILCMPIMNAQKKVIGVAQLINKANGVPFTDSD--------ASIFEAFAIFCGLGIHNTQMYENAC 622
                               .|.::......||        |...::.|.|.|..:| ..::....
 Frog   505 -------------------TNHSDSSDILPSDEPDGAKDPAQSRKSSASFQGEVLH-PLIHSEEK 549

  Fly   623 KLMAKQKVALECLSYHATASQDQTEKLTQDVIAEAESYNLYSFTFTDFELVD---DDTCRAV--- 681
            .::|.:.:.:|.|               ..::.|..::|     |..|:||:   ..|.|.:
 Frog   550 AVLAPEPLLMEDL---------------DSLMGEINNWN-----FPIFDLVEKTGQKTGRILSQV 594

  Fly   682 -LRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMF------------AM 733
             .|:|....|:..|:||......:..::...||.:.|||..||.:|...::            |:
 Frog   595 SYRLFEDMGLLETFKIPLREFMNYFHALESGYRDIPYHNRIHATDVLHAVWYLSTQAIPGLPNAV 659

  Fly   734 LKTGKMERFMTD--------------------------------LEILGLLVACLCHDLDHRGTN 766
            .:.|......:|                                ||::.|.||...||.||.|..
 Frog   660 SEQGSASDSDSDSGITHGHMGYVFSKMYNPSDDTYGCLSGNIPSLELMALYVAAAMHDYDHPGRT 724

  Fly   767 NAFQTKTESPLAILYT-TSTMEHHHFDQC-VMILNSEGNNIFQALSPEDYRSVMKTVESAILSTD 829
            |||...|.:|.|:||. .|.:|:||.... .:.|:....|....|...:::.....|..|||:||
 Frog   725 NAFLVATNAPQAVLYNDRSVLENHHAAAAWNLFLSRPEYNFLVNLDHMEFKRFRFLVIEAILATD 789

  Fly   830 LAMYFKKRNAFLELVENGE----FDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADE 890
            |..:|.....|...| |||    .||..|..:.|:|.|.:...|::..||..::..|..:.:.:|
 Frog   790 LKKHFDFLAEFNAKV-NGEVSPGIDWSNENDRLLVCQMCIKLADINGPAKFKDLHLKWTEGIVNE 853

  Fly   891 FFDQGDLE-KLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLEN 954
            |::|||.| .|.|...|  .|||. ..:|.|:|..||..|..|    ||.::
 Frog   854 FYEQGDEESSLGLPISP--FMDRS-APQLAKLQESFITHIVGP----LCHSY------------- 898

  Fly   955 RRNWQDLAEKVEMGL---TWIDHDTIDKPVEEFAACADE--EIKDIEFTVTTLNCNQQSQHGSED 1014
                 |.|     ||   .|:|.             :||  |..|.:        .|:.:...|:
 Frog   899 -----DSA-----GLMPGKWLDE-------------SDERDESDDTD--------EQEEEDTEEE 932

  Fly  1015 SHTPEHQRSGSRLSMKKTGALGKAVRSKLSKTLYNSMDGSKPKTSLK---------LLESH---- 1066
            |..|.          :...::...:...|...|:.|..|.:.|...:         |:|:|
 Frog   933 SSEPN----------ESLASMSSLILCCLKDALWGSNAGKEKKKCKRKIYCQITQHLMENHKMWK 987

  Fly  1067 -VSEDMDDKSPTSPSQPQA 1084
             |.|| :...|.|..|.||
 Frog   988 KVMED-EQLEPKSSEQIQA 1005

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde6	NP_001262566.1	GAF	247..406	CDD:214500
		GAF	431..619	CDD:214500	24/125 (19%)
		PDEase_I	717..950	CDD:278654	78/283 (28%)
pde3a	XP_031753954.1	PRK07764	<19..209	CDD:236090
		PDEase_I	631..894	CDD:395177	76/270 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010