Protein Alignment Pde6 and pde6b

DIOPT Version :9

• Sequence 1: NP_001262566.1
• Gene: Pde6 / 41760
• FlyBaseID: FBgn0038237
• Length: 1124
• Species: Drosophila melanogaster
• Sequence 2: XP_012808736.2
• Gene: pde6b / 100487945
• XenbaseID: XB-GENE-961019
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 916
• Identity: 288/916 - (31%)
• Similarity: 464/916 - (50%)
• Gaps: 142/916 - (15%)

  Fly   133 KASTTASQQDVDEVARLFEEKPEAFEKWLTERAPPEALSRLQEFIENRKPHKRPSVTSDLFQQWM 197
            |||.|     :::||...:..|...:::..::..||.::         ....|..:|.| |..:
 Frog     5 KASLT-----LEDVANYMDNNPAFTQRYFEKKLKPETIA---------AAFGRKDLTVD-FATF- 53

  Fly   198 AASPTVQQKSPRSLSNSSASSLPECRRHLMDLDEGELFMELIRDVANELDIDVLCHKILVNVGLL 262
                                      |.|:.::|.|:..||:.|:...::::.:..|.|..:..|
 Frog    54 --------------------------RELVQVEESEILFELVNDMQESINMEKVVFKTLRRISFL 92

  Fly   263 THADRGSLFLAK---GTPTNKYLVAKLFDVTQKTALKDAVTRASAEEIIIPFGIGIAGMVAQTKQ 324
            .||||.|||:.:   |||.   |..:||:|...:.|::.:....: ||:.|..|||.|.||.||:
 Frog    93 IHADRCSLFMYRQRNGTPE---LATRLFNVKSNSKLEECLVPPDS-EIVYPLDIGIVGHVAHTKK 153

  Fly   325 MINIKEAYKDARFNCEIDLKTGYKTNAILCMPICNYEGDIIGVAQIINKTNGCMEFDEHDVEIFR 389
            .||:|:..:...::...|..|.|:|..||..||.|.: |::.|...:||.:|.. |..:|.|:|.
 Frog   154 TINVKDVSECTVYSKFADELTDYETKNILATPILNGK-DVVAVIMAVNKLDGPF-FTNYDEEVFL 216

  Fly   390 RYLTFCGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSV 454
            :||.|..:.::...|..:...|.||.|:||..|..:|||..::|....|.....|..|.|:|.||
 Frog   217 KYLNFASLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSV 281

  Fly   455 FLVDLDCCEASHLEKIIEK------------------PNQPATRAI---KSADSFEEKKMRNRFT 498
            .|:|:          ..||                  |..|..|.|   |..|
 Frog   282 GLLDM----------TKEKEFFDVWPVLMGEVPPYTGPRTPDGREIVFYKVID------------ 324

  Fly   499 VLFELGGEYQAANVSRPSVSELSSSTLAQIAQFVATTGQTVNICDVIEWVRDHNQIRAEDEIDST 563
              :.|.|:.....:..|.....  :.::.:..:||.:|   .||:::....|......::.:|.:
 Frog   325 --YILHGKEDIKVIPNPPADHW--ALVSGLPTYVAESG---FICNIMNAGADEMFKFQKEPLDES 382

  Fly   564 ----QAILCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKL 624
                :.:|.|||:|.:::::|||...|:.:|.||.:.|.::.|:...|.|..:.||..::...||
 Frog   383 GWVVKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEQDETLMESLTQFLGWSVLNTDTHDKMNKL 447

  Fly   625 MAKQKVALECLSYHATASQDQ-------TEKLTQDVIAEAE----------------SYNLYSFT 666
            ..::.:|.:.:.||....:|:       .|||.::| .|.|                .:.:|.|.
 Frog   448 ENRKDIAQDMVMYHVKCDKDEIQDILPTREKLGKEV-TECEEDEIAKTLKQVLPGPTKFEIYEFR 511

  Fly   667 FTDFELVDDDTCRAVLRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMF 731
            |:||:..:.|..:..::|:.:..:|.:||:|.:.|.|::.:::|.||.|.||||||..|||||||
 Frog   512 FSDFDCTEIDLVKCGIQMYYELGVVKKFQVPPEALVRFMYAMKKGYRRVTYHNWRHGFNVAQTMF 576

  Fly   732 AMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTTSTMEHHHFDQCVM 796
            .:|.|||::|:.||||.:.::.|..|||:|||||||.:|.|::.|||.|:.:|.:|.||.:....
 Frog   577 TLLMTGKLKRYYTDLEAMAMVTAGFCHDIDHRGTNNLYQMKSQHPLAKLHGSSILERHHLEFGKF 641

  Fly   797 ILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEK----- 856
            :|..|..||||.|:...:..|:..::.||::||||:|||||..|.::|:..: .::.|:|
 Frog   642 LLADESMNIFQNLNRRQHEHVIHLMDIAIIATDLALYFKKRTMFQKIVDQSK-TYEDEQKWTEYL 705

  Fly   857 ------KDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERK 915
                  |:::..|||||||:|||.||||||.|||.|||.||::|||||:..|..||:.||||.:.
 Frog   706 SLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLQQQPIPMMDRNKS 770

  Fly   916 DELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLAEKVEMGLTWIDHDTIDKP 980
            .||||:|.||||.:|..:|:........|.|:.:|.|.||:.|:.||::.|..:..::.:. .|.
 Frog   771 AELPKLQCGFIDFVCTFVYKEFARFHEEIQPMLDGLLNNRKEWKALADEYEAKVKTVEEEK-KKR 834

  Fly   981 VEEFAA 986
            .||.||
 Frog   835 EEELAA 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde6	NP_001262566.1	GAF	247..406	CDD:214500	54/161 (34%)
		GAF	431..619	CDD:214500	46/212 (22%)
		PDEase_I	717..950	CDD:278654	116/243 (48%)
pde6b	XP_012808736.2	GAF	77..236	CDD:214500	54/164 (33%)
		GAF	258..445	CDD:214500	46/215 (21%)
		PDEase_I	562..806	CDD:365964	116/244 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56437
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11347
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.030