Protein Alignment Cyp313a1 and CYP4F2

DIOPT Version :9

• Sequence 1: NP_650368.1
• Gene: Cyp313a1 / 41759
• FlyBaseID: FBgn0038236
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001073.3
• Gene: CYP4F2 / 8529
• HGNCID: 2645
• Length: 520
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 125/507 - (24%)
• Similarity: 213/507 - (42%)
• Gaps: 87/507 - (17%)

  Fly     6 LLLAVGA-------LFWIYFLWSR-----------RRLYFL----MLKIPGPIGLPILGSSLENI 48
            |||.|||       |.|.|..:..           ||.:|.    |:. |...|:.:|
Human    21 LLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWFWGHQGMVN-PTEEGMRVL------- 77

  Fly    49 ITYKRKLSFRTKYLNKYGSTILTWMGPV-PFIVTRDPKVVEDIF-SSPDCHNKSQHIVNAITSCM 111
                      |:.:..|......||||: |.:....|.::..:. :|.....|.:...:.:...:
Human    78 ----------TQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWL 132

  Fly   112 GNGLLGKQDPHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGE--IDVVPEMLR 174
            |:|||......|...|:...|:|..::|..:..||:....::.........:|.  :|:
Human   133 GDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDM------ 191

  Fly   175 WSFKIAAQTTMGSEVKHDEHFKNGSLVESFESLISHSTLNILMPLVQ-NRMISKICGYDKLRAD- 237
              |:..:..|:.|..|         .|.||:|.........:..::: :.::||......|..|
Human   192 --FEHISLMTLDSLQK---------CVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILLHIDF 245

  Fly   238 ---------NFSR----IQKMLDNVVNKKVNPLPKTDSD-------PESNIVINRAMELYRKGD- 281
                     .|.|    :....|.|:.::...||....|       ....:.....:.|.:..|
Human   246 LYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDG 310

  Fly   282 --ITYMDVKSECCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDM 344
              ::..|:::|....:..|:||:|..:...|:.||.|||:||...:|:..:..|.....|.:.|:
Human   311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDL 375

  Fly   345 QKLDYLERVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADN 409
            ..|.:|...:||:|||.|.:|:.:|....|:.|.:|.:||||::..|.:|.||.||.|| ||.:.
Human   376 AHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEV 439

  Fly   410 FNPDNFLAENMEQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKI 461
            ::|..|..||::::.|.|:|||:.|.|||||..:||...|..|...|..:::
Human   440 YDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRV 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	112/458 (24%)
CYP4F2	NP_001073.3	DUF4175	4..>57	CDD:372724	9/35 (26%)
		p450	52..515	CDD:365848	116/476 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810