DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp313a1 and CYP81F4

DIOPT Version :9

Sequence 1:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_195457.1	Gene:	CYP81F4 / 829895	AraportID:	AT4G37410	Length:	501	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	121/521 - (23%)
Similarity:	218/521 - (41%)	Gaps:	84/521 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 INLLLAVGALFWIYFLWSRRRLYFLMLKIPGP-IGLPILG----------------SSLENIITY 51
            |.|.||:..|.:.:|..|:::.|:|.   |.| ..|||||                |::...|.|
plant     6 IILPLALFLLAYKFFFTSKKQRYYLP---PSPSYSLPILGHHLLIKPPVHRLFHRLSNIHGPIFY 67

  Fly    52 KRKLSFRTKYLNKYGSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMGNGLL 116
            .|..|.|...::........:.|....||:..|:.:...:.       :.:.....|:..|:
plant    68 LRLGSRRAVVISSSSLARECFTGQNDVIVSNRPRFLTSKYI-------AYNYTTIATTSYGD--- 122

  Fly   117 GKQDPHWLDRRKHFN---PSFKQDLLLSFFHIFDAETKVLMNLL--DTYVDKGEIDVVPEMLRWS 176
                 ||.:.|:..:   .|.|:  |.:|.||...|.:.::..|  |..|.| |:::...:...:
plant   123 -----HWRNLRRICSLEIVSSKR--LANFLHIRKEEIQRMLTRLSRDARVGK-EVELESILYDLT 179

  Fly   177 FK-----IAAQTTMGSEVKHDEHFKNGSLVESFESLISHSTLNILMPLVQNRMISKICGYDKLRA 236
            |.     :..:...|.:|...|.      .|.|:.|.:..|.|     ...|...:...:.|:..
plant   180 FNNIVRMVTGKIYYGDDVSDKEE------AELFKKLFTFITTN-----SGARHPGEYLPFMKIFG 233

  Fly   237 DNFSRIQKMLDNVVNKKVNP-LPKTDSDPESNIVINRAMELYRKGDITYMD--VKSECCIMIAAG 298
            .:|.:..|....|:::.:.. |.:..||.:.|.::|..:.|.:.....|.|  :|.....::.|.
plant   234 GSFEKEVKAAAKVIDEMLQRLLDECKSDKDGNTMVNHLLSLQQDDPEYYTDIIIKGLMLGIMVAS 298

  Fly   299 YDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFG----ITYPDMQKLDYLERVIKETLR 359
            .:|||||:..|:..|.|||:..:.|..|::.:      .|    |...|:..|.||:.|:.||||
plant   299 SETSALTIEWAMASLLNHPKVLDKVKLEIDEI------IGQDRLIEESDIANLPYLQNVVSETLR 357

  Fly   360 LIPAIPI-TARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAENMEQK 423
            |.||.|: ..|.|..|::: .|..:|:..::.::.:..||:|::| .:.:.|||:.|.....|:.
plant   358 LHPAAPVLVPRSTAEDIKI-GGYDVPRDTMVMVNAWAIHRDPDLW-TEPERFNPERFNGGEGEKD 420

  Fly   424 HPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLYKDLVYVDNMTMKLAEYPRLKL 488
            .....|.|..|:|.|.|...|......||..:::.:         |...|:...:.::|.|.:.:
plant   421 DVRMLIAFGSGRRICPGVGLAHKIVTLALGSLIQCF---------DWKKVNEKEIDMSEGPGMAM 476

  Fly   489 Q 489
            :
plant   477 R 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	108/464 (23%)
CYP81F4	NP_195457.1	CYP81	63..482	CDD:410746	104/461 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000