DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp313a1 and CYP72A11

DIOPT Version :9

Sequence 1:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_188083.1	Gene:	CYP72A11 / 820693	AraportID:	AT3G14650	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	123/521 - (23%)
Similarity:	223/521 - (42%)	Gaps:	84/521 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LTINLLLAVGALFWIY----FLWSRRRLYFLMLKIPGPIG---LPILGSSLENIITYKRKLSFRT 59
            :|:::.:.| ..:|::    ::|.:.::....|:..|..|   .|::|...:|   :..:...|:
plant     8 VTVSVAVVV-VSWWVWRTLQWVWFKPKMLESYLRRQGLAGTPYTPLVGDLKKN---FSMRAEARS 68

  Fly    60 KYLN------------------KYGSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNA 106
            |.:|                  .:|.|..||.|.:|.|...||:.:.::.      ||......|
plant    69 KPINLTDDITPRIVPYPLQMLKTHGRTFFTWFGAIPTITIMDPEQITEVL------NKVYDFQKA 127

  Fly   107 ITSCMG----NGLLGKQDPHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYV-DKG-- 164
            .|..:|    .|:|......|...|:..||:|..:.:.:....|......::...|..| ||.
plant   128 HTFPLGRLIATGVLSYDGDKWAKHRRIINPAFHLEKIKNMVPAFHQSCSEIVCKWDKLVSDKESS 192

  Fly   165 -EIDVVPEMLRWSFKIAAQTTMGSEVKHDEHFKNGSLVES---FESLISHSTLNILMPLVQNRMI 225
             |:||.|.::..:..:.::|..||           |.||.   ||  :......:::..|:...|
plant   193 CEVDVWPGLVSMTADVISRTAFGS-----------SCVEGQRIFE--LQAELAQLIIQTVRKAFI 244

  Fly   226 SKICGYDKLRADNFSR-------IQKMLDNVVNKKV--NPLPKTDSDPESNIVINRAMELYRKGD 281
            .   ||..|......|       ||.:|..:|||::  ....:..:|....|::...:...:...
plant   245 P---GYSYLPTKGNRRMKAKAREIQVILRGIVNKRLRAREAGEAPNDDLLGILLESNLGQTKGNG 306

  Fly   282 ITYMDVKSECCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQK 346
            ::..|:..||.:....|.:|:::.:...:.||:.|.:.|....||:..||.|      ..||.:.
plant   307 MSTEDLMEECKLFYFVGQETTSVLLVWTMVLLSQHQDWQARAREEVKQVFGD------KEPDAEG 365

  Fly   347 LDYLE---RVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDAD 408
            |:.|:   .::.|.|||.|.||..:|....::.|.: :.:|.||:|.:.:....|:.|:||.||.
plant   366 LNQLKVMTMILYEVLRLYPPIPQLSRAIHKEMELGD-LTLPGGVLINLPILLVQRDTELWGNDAG 429

  Fly   409 NFNPDNFLAENMEQ--KHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLYKDLV 471
            .|.||.| .:.:.:  |:..::.|||.|.|.|||..:|::.:|.|:..||:.:....|..|....
plant   430 EFKPDRF-KDGLSKATKNQASFFPFAWGSRICIGQNFALLEAKMAMALILQRFSFELSPSYVHAP 493

  Fly   472 Y 472
            |
plant   494 Y 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	115/475 (24%)
CYP72A11	NP_188083.1	p450	24..512	CDD:299894	120/504 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.970