DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a1 and CYP72A9

DIOPT Version :9

Sequence 1:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_188081.2	Gene:	CYP72A9 / 820691	AraportID:	AT3G14630	Length:	563	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	120/507 - (23%)
Similarity:	225/507 - (44%)	Gaps:	76/507 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LAVGALFW-----IYFLWSRRRLYFLMLKIPGPIG---LPILG-----------------SSLEN 47
            ||:..:.|     :.::|.:.::....|:..|.:|   .|::|                 ...::
plant    63 LALVVVLWCIWRILEWVWLKPKMLESYLRRQGLVGTRYTPLVGDVRRSFSMLKEARSKPMKPTDD 127

  Fly    48 IITYKRKLSFRTKYLNKYGSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMG 112
            :|:.....||.  .||.||.|..||.||:|.|...:|::::::::......|:...  .:||.:.
plant   128 LISLVMPYSFH--MLNTYGKTFFTWSGPIPAITIMNPQLIKEVYNKFYDFEKTHTF--PLTSLLT 188

  Fly   113 NGLLGKQDPHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYV-DKG---EIDVVPEML 173
            :||.......|:..||..||:|..:.:.:....|......:|...:..| |||   |:||.|.::
plant   189 DGLANADGDKWVKHRKIINPAFHFEKIKNMVPTFYKSCIEVMCEWEKLVSDKGSSCELDVWPWIV 253

  Fly   174 RWSFKIAAQTTMGSEVKHDEHFKNGSLVESFESLISHSTLNIL----------MPLVQNRMISKI 228
            ..:..:.::|..||.      :|.|..:...::.::|..:..|          .|...||.:..|
plant   254 NMTGDVISRTAFGSS------YKEGQRIFILQAELAHLIILALGKNYIPAYRHFPTKNNRRMKTI 312

  Fly   229 CGYDKLRADNFSRIQKMLDNVVN--KKVNPLPKTDSDPESNIVINRAMELYRKGDITYMDVKSEC 291
                      ...||.:|..:::  :|.....:..||....|::....|..:...:...::..||
plant   313 ----------VKEIQVILRGIISHREKARDAGEAPSDDLLGILLKSNSEQSKGNGLNMEEIMEEC 367

  Fly   292 CIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLE---RV 353
            .:...||.:|:::.:...:.||:.|.:.|....||:..||   ||   ..||:|.::.|:   .:
plant   368 KLFYFAGQETTSVLLAWTMVLLSQHQDWQARAREEVMQVF---GH---NKPDLQGINQLKVMTMI 426

  Fly   354 IKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNF--- 415
            |.|.|||.|.:....|.|..:::|.: :.:|.|:.:.:.:...||:.::||.||..|.|:.|
plant   427 IYEVLRLYPPVIQMNRATHKEIKLGD-MTLPGGIQVHMPVLLIHRDTKLWGDDAAEFKPERFKDG 490

  Fly   416 LAENMEQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLY 467
            :|:  ..|:...::||..|.|.|||..:|::.:|.||..||:.:....|..|
plant   491 IAK--ATKNQVCFLPFGWGPRICIGQNFALLEAKMALALILQRFSFELSPSY 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	113/471 (24%)
CYP72A9	NP_188081.2	p450	59..563	CDD:386267	120/507 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.970