DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp313a1 and CYP72A8

DIOPT Version :9

Sequence 1:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_188080.1	Gene:	CYP72A8 / 820690	AraportID:	AT3G14620	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	115/514 - (22%)
Similarity:	202/514 - (39%)	Gaps:	106/514 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 WIY----FLWSRRRLYFLMLKIPGPIGLP---ILG------SSLENIITYKRKLSFRTKYLNK-- 64
            ||:    ..|.|.:.....||..|..|.|   ::|      |.:|.  ...|.::....|.::
plant    24 WIWKGLNVAWLRPKKNEAYLKRQGLSGTPFTFLVGDIKREASMVEQ--EKSRPINLTDDYTHRVM 86

  Fly    65 ---------YGSTILTWMGPVPFIVTRDPKVVEDI------FSSPDCHNKSQHIVNAITSCMGNG 114
                     :|.|...||||:..::...|:.::|:      |..|..|        .|......|
plant    87 PLIQQTVKDHGKTSYMWMGPIASVIVTKPEHIKDVLNRVYDFPKPPVH--------PIVELFATG 143

  Fly   115 LLGKQDPHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYV----DKGEIDVVPEMLRW 175
            :...:...|...||..||||..:.|......|......:::..:..|    ...||||.|.:...
plant   144 VALYEGEKWSKHRKIINPSFHLEKLKIMIPAFYESCSEMISKWEKLVTEQGSSNEIDVWPYLGDL 208

  Fly   176 SFKIAAQTTMGSEVKHDEHFKNGSLVESFESLISHSTLNIL----------MPLVQN---RMISK 227
            :..:.::|..||.      ::.|..:...:.......|..|          :|...|   |.|:|
plant   209 TSDVISRTAFGSS------YEEGKRIFELQEEQGRRVLKALELAFIPGMRFLPTKNNLRMRQINK 267

  Fly   228 ICGYDKLRADNFSRIQKMLDNVVNKK-----VNPLPKTDSDPESNIVINRAMELYRKGD--ITYM 285
                         .::..|..::.|:     ....||.|       ::...:| ...||  ::..
plant   268 -------------EVKSRLREIIMKRQRGMDTGEAPKND-------LLGILLE-SNSGDHGMSIE 311

  Fly   286 DVKSECCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVF-----PDAGHFGITYPDMQ 345
            ||..||.:...||.:|:|:.:...:.:|::|.:.|:...||:..|.     |:       :..:.
plant   312 DVVEECRLFHFAGQETTAVLLVWTMIMLSHHQKWQDQAREEILKVIGKNNKPN-------FDALS 369

  Fly   346 KLDYLERVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNF 410
            :|..:..::.|.|||.|...:..|..:.:.:|...:.:|.|..:.|.:...||:||:||.|...|
plant   370 RLKTMSMILNEVLRLYPPGILLGRTVEKETKLGEDMTLPGGAQVVIPVLMVHRDPELWGEDVHEF 434

  Fly   411 NPDNFLAENMEQ--KHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLY 467
            ||:.| |:.:.:  |:..:::||..|.|.|.|..:|:|.:|.||..||:.:....|..|
plant   435 NPERF-ADGISKATKNQVSFLPFGWGPRFCPGQNFALMEAKMALVLILQRFSFELSPSY 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	107/486 (22%)
CYP72A8	NP_188080.1	p450	26..515	CDD:299894	113/512 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.970