DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a1 and KAO2

DIOPT Version :9

Sequence 1:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001189657.1	Gene:	KAO2 / 817805	AraportID:	AT2G32440	Length:	489	Species:	Arabidopsis thaliana

Alignment Length:	511	Identity:	113/511 - (22%)
Similarity:	199/511 - (38%)	Gaps:	140/511 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 WIYFLWSRRRLYFLMLKIPGPIGLPILGSSLENIITYKRK--LSFRTKYLNKYGSTIL--TWMGP 75
            |||......:.::|.   ||.:|.|::|:....:..:|..  .||...|:.:||.|.:  ..|..
plant    31 WIYVSKLGEKKHYLP---PGDLGWPVIGNMWSFLRAFKTSDPESFIQSYITRYGRTGIYKAHMFG 92

  Fly    76 VPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMGNGLLG--KQDPHWLDRRKHFNPSFKQDL 138
            .|.::...|:....:.:..|..:                 :|  |.....:.|:.....||::..
plant    93 YPCVLVTTPETCRRVLTDDDAFH-----------------IGWPKSTMKLIGRKSFVGISFEEHK 140

  Fly   139 --------------LLSFFHIFDAETKVLMNL-LDTYVDKGEIDVVPEMLRWSFKIAAQTTMGSE 188
                          .||.:..|..||   :|. |:.:...|||:.:..:.:.:||:.....:.||
plant   141 RLRRLTSAPVNGPEALSVYIQFIEET---VNTDLEKWSKMGEIEFLSHLRKLTFKVIMYIFLSSE 202

  Fly   189 VKH-----DEHFKN------------------------GSLVESFESLISHSTLNILMPLVQNRM 224
            .:|     :..:.|                        ..||.:|:|:::            ||.
plant   203 SEHVMDSLEREYTNLNYGVRAMGINLPGFAYHRALKARKKLVAAFQSIVT------------NRR 255

  Fly   225 ISKICGYDKLRADNFSRIQK-MLDNVVNKKVNPLPKTDSDPESNIVINRAMELYRKGDITYMDVK 288
                    ..|..|.|..:| ||||:::.|          .|:..|::         |...:|:
plant   256 --------NQRKQNISSNRKDMLDNLIDVK----------DENGRVLD---------DEEIIDL- 292

  Fly   289 SECCIMIAAGYDTSALTVYHALFLLANHP-------EHQEAVFEELNGVFPDAGHFGITYPDMQK 346
              ..:.:.||:::|......|..|:..||       |.||.:.::      .|....:|..:.::
plant   293 --LLMYLNAGHESSGHLTMWATILMQEHPMILQKAKEEQERIVKK------RAPGQKLTLKETRE 349

  Fly   347 LDYLERVIKETLRLIPAIPITA-RETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNF 410
            :.||.:||.||||:| ...:|| ||.|:||:: :|.:||||..:.....:.|.:||:: ||...|
plant   350 MVYLSQVIDETLRVI-TFSLTAFREAKSDVQM-DGYIIPKGWKVLTWFRNVHLDPEIY-PDPKKF 411

  Fly   411 NPDNFLAENMEQKHPYA--YIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTS 464
            :|..:     |...|.|  ::||..|...|.|:..|.:.....|...|..|::..|
plant   412 DPSRW-----EGYTPKAGTFLPFGLGSHLCPGNDLAKLEISIFLHHFLLKYRVERS 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	108/490 (22%)
KAO2	NP_001189657.1	PLN02302	2..489	CDD:215171	113/511 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010