DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp313a1 and BAS1

DIOPT Version :9

Sequence 1:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_180239.1	Gene:	BAS1 / 817212	AraportID:	AT2G26710	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	527	Identity:	133/527 - (25%)
Similarity:	233/527 - (44%)	Gaps:	86/527 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 INLLLAVG-ALFWIYFLWSRRRL--YFLMLKIPGP------------IGLPILGSS-----LENI 48
            ::|::..| :|.|    |..|::  :|....|.||            :|:.:..||     ..||
plant    20 LSLVIVKGMSLLW----WRPRKIEEHFSKQGIRGPPYHFFIGNVKELVGMMLKASSHPMPFSHNI 80

  Fly    49 ITYKRKLSFRTKYLNKYGSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQ-HIVNAITSCMG 112
            :  .|.|||...:...||:|.|.|.||...:...||.::.:|||..:.:.|:: |.:  :....|
plant    81 L--PRVLSFYHHWRKIYGATFLVWFGPTFRLTVADPDLIREIFSKSEFYEKNEAHPL--VKQLEG 141

  Fly   113 NGLLGKQDPHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDK----GEIDVVPEML 173
            :|||..:...|...||..:|:|..:.|.....:.   .|.:.:::|.:.||    ||::|  ::.
plant   142 DGLLSLKGEKWAHHRKIISPTFHMENLKLLVPVV---LKSVTDMVDKWSDKLSENGEVEV--DVY 201

  Fly   174 RWSFKI-----AAQTTMGSEVKHDEHFKNGSLVESFES----LISHSTLNILMP---LVQNRMIS 226
            .| |:|     .::|..||.      :::|..|...::    |.:.:...:.:|   ....|...
plant   202 EW-FQILTEDVISRTAFGSS------YEDGRAVFRLQAQQMLLCAEAFQKVFIPGYRFFPTRGNL 259

  Fly   227 KICGYDK-LRADNFSRIQKMLDNVVNKKVNPLPKTDSDPESNIVINRAMELYRKGDITYMDVKSE 290
            |....|| :|......|::...|.::.:    .:...:|.:..::..   :.:..::|..|:..|
plant   260 KSWKLDKEIRKSLLKLIERRRQNAIDGE----GEECKEPAAKDLLGL---MIQAKNVTVQDIVEE 317

  Fly   291 CCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGV-----FPDAGHFGITYPDMQKLDYL 350
            |.....||..|::..:.....||:.|||.|....:|:..|     .|...|       :.||..|
plant   318 CKSFFFAGKQTTSNLLTWTTILLSMHPEWQAKARDEVLRVCGSRDVPTKDH-------VVKLKTL 375

  Fly   351 ERVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNF 415
            ..::.|:|||.|.|..|.|..|:||:| .|..||.|..:.|.:...|.:..:||.|.:.|||..|
plant   376 SMILNESLRLYPPIVATIRRAKSDVKL-GGYKIPCGTELLIPIIAVHHDQAIWGNDVNEFNPARF 439

  Fly   416 LAENMEQ--KHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLYKDLVYVDNMTM 478
             |:.:.:  |||..:|||..|.|.|||...|::.:|..|..:::.:....:..|:   :...:.|
plant   440 -ADGVPRAAKHPVGFIPFGLGVRTCIGQNLAILQAKLTLAVMIQRFTFHLAPTYQ---HAPTVLM 500

  Fly   479 KLAEYPR 485
            .|  ||:
plant   501 LL--YPQ 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	120/471 (25%)
BAS1	NP_180239.1	CYP734	85..509	CDD:410732	117/456 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.970