Protein Alignment Cyp313a1 and cyp46a1.2

DIOPT Version :10

• Sequence 1: NP_650368.1
• Gene: Cyp313a1 / 41759
• FlyBaseID: FBgn0038236
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001072550.1
• Gene: cyp46a1.2 / 780005
• XenbaseID: XB-GENE-5802444
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 517
• Identity: 125/517 - (24%)
• Similarity: 221/517 - (42%)
• Gaps: 103/517 - (19%)

  Fly     6 LLLAVGALFWIYFLWSRRRLYFLMLK---IPGPIGLP----ILGSSL-------ENIITYKRKLS 56
            |||   ||..|.||.....::::.:|   ||||   |    |.|.|.       ||::.|    .
 Frog    13 LLL---ALILICFLLYCGYIHYIHMKYDHIPGP---PRDSFIFGHSTALLKLVNENLLMY----D 67

  Fly    57 FRTKYLNKYGSTI-LTWMGPVPFIVTRDPKVVEDIFSSPD-CHNKSQHIVNAI--TSCMGNGLLG 117
            :...:::|||..: :..:..|..:|. .|:.:::...||. ..::......::  ...||.|||.
 Frog    68 YFLDWVHKYGPVMRINGLHKVAVLVA-SPEGIKEFLMSPKYLKDEFYDFFGSLFGERLMGKGLLT 131

  Fly   118 KQD-PHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVD-KGEIDVVPEMLRWSFKIA 180
            .:| .||..:|:..:|:|.:..|:.....|:.:.:.||..|....| |.|:::.....:.:..:.
 Frog   132 DRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLSENSDRKCEVNMHDMFSKVTLDVI 196

  Fly   181 AQTTMGSEVK--HDEHFKNGSLVESFESLISHSTLNILMPLVQNRMISKICGYDKLRADNFSRIQ 243
            .:...|.|:.  :|:.......:    ||:...::.|..|:::                 :|..:
 Frog   197 GKVGFGMELNSLNDDQTPFPRAI----SLVMKGSVEIRNPMIK-----------------YSLAK 240

  Fly   244 KMLDNVVNKKVNPLPKTDSDPESNIVINRAMELYRKGDITYMDV----------KSEC------- 291
            :.|...|.:.:..|.:|..:     .|.|..:..:.|:...:|:          :.:|
 Frog   241 RGLIRKVQESIRLLRQTGKE-----CIERRQKQIQDGEEIPVDILTQILRGTALEKDCDPETLLD 300

  Fly   292 --CIMIAAGYDTSALTVYHALFLLANHPE---HQEAVFEELNGVFPDAGHFGITYPDMQKLDYLE 351
              .....||.:|:|..:..|:..|..:||   ..:|..:|:.|...|     |.|.|:.||.||.
 Frog   301 NFVTFFIAGQETTANQLSFAVMSLGRNPEILKKAQAEIDEVIGSKRD-----IEYEDLGKLSYLS 360

  Fly   352 RVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFL 416
            :|:||||||.|..|.|:|..:|::.:.. |.||..|.:.::.:...| .|.:..|...||||.|
 Frog   361 QVLKETLRLYPTAPGTSRTLENEIVIDE-VRIPGNVTLMLNSYVMGR-MEQYYKDPLMFNPDRF- 422

  Fly   417 AENMEQKHPY-AYIPFARGKRNCIGSKYAMMSSKFALCRILRNYK-----------ISTSTL 466
              :.:...|| .|.||:.|.|||||..::.|.:|..:.:.|:.|:           :.|.||
 Frog   423 --SPDAPKPYFTYFPFSLGPRNCIGQVFSQMEAKVVMAKFLQRYEFELAEGQSFKILDTGTL 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	CYP313-like	66..487	CDD:410680	103/443 (23%)
cyp46a1.2	NP_001072550.1	CYP46A1-like	66..490	CDD:410706	106/458 (23%)