Protein Alignment Cyp313a1 and CYP4F12

DIOPT Version :9

• Sequence 1: NP_650368.1
• Gene: Cyp313a1 / 41759
• FlyBaseID: FBgn0038236
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_076433.3
• Gene: CYP4F12 / 66002
• HGNCID: 18857
• Length: 524
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 126/492 - (25%)
• Similarity: 212/492 - (43%)
• Gaps: 60/492 - (12%)

  Fly     6 LLLAVGA------LFWIYFLWSRRRLYFLMLKIP------GPIGLPILGSSLENIITYKRKLSFR 58
            |||.||:      |.|.|..::..|......:.|      |.:||         |...:..|...
Human    22 LLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWFWGHLGL---------ITPTEEGLKNS 77

  Fly    59 TKYLNKYGSTILTWMGP-VPFIVTRDPKVVEDIF-SSPDCHNKSQHIVNAITSCMGNGLLGKQDP 121
            |:....|......|:|| :||||...|..:..|. :|.....|....:..:...:|.|:|.....
Human    78 TQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGD 142

  Fly   122 HWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKG--EIDVVPEMLRWSFKIAAQTT 184
            .|...|:...|:|..::|.|:..||:....::::.......:|  .:|:        |:..:..|
Human   143 KWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDM--------FEHISLMT 199

  Fly   185 MGSEVK----HDEHFKN------GSLVESFESLISHSTLNILMPLVQNRMISKICGYDKLRADNF 239
            :.|..|    .|.|.:.      .:::| ..:|:...:.:||    |:........:|..|....
Human   200 LDSLQKCIFSFDSHCQERPSEYIATILE-LSALVEKRSQHIL----QHMDFLYYLSHDGRRFHRA 259

  Fly   240 SR-IQKMLDNVVNKKVNPLPK-------TDSDPESNIVINRAMELYRKGD---ITYMDVKSECCI 293
            .| :....|.|:.::...||.       .|......:.....:.|.:..|   ::..|:::|...
Human   260 CRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADT 324

  Fly   294 MIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLERVIKETL 358
            .:..|:||:|..:...|:.||.|||:||...:|:..:..|.....|.:.|:.:|.:|...:||:|
Human   325 FMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESL 389

  Fly   359 RLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAENMEQK 423
            ||.|..|..:|....|:.|.:|.:||||:...||:...|.||.|| ||.:.::|..|..||.:.:
Human   390 RLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVW-PDPEVYDPFRFDPENSKGR 453

  Fly   424 HPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYK 460
            .|.|:|||:.|.|||||..:||...|..|..:|.:::
Human   454 SPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFR 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	117/459 (25%)
CYP4F12	NP_076433.3	p450	52..506	CDD:306555	117/462 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810