Protein Alignment Cyp313a1 and Cyp3a57

DIOPT Version :10

• Sequence 1: NP_650368.1
• Gene: Cyp313a1 / 41759
• FlyBaseID: FBgn0038236
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 500
• Identity: 134/500 - (26%)
• Similarity: 228/500 - (45%)
• Gaps: 66/500 - (13%)

  Fly     6 LLLAVGALFWIYFLWSRRRLYFLMLKIPGPIGLPILGSSLENIITYKRKL-SFRTKYLNKYGSTI 69
            ||:.....|:||..:|..  .|..|.||||..||:.|    |||.|...: .|......|||...
Mouse    14 LLVTSLVFFYIYGTYSHG--LFKKLGIPGPKPLPLFG----NIINYLDGMWKFDDDCYKKYGKIW 72

  Fly    70 LTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMGNGLLG--------KQDPHWLDR 126
            ..:.||.|.:...||:::: |....:|:       :..|:....|.:|        .:|..|...
Mouse    73 GFYEGPQPILAIMDPEIIK-IVLVKECY-------SVFTNRRPFGPVGFLKKSITISEDEEWKRL 129

  Fly   127 RKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGE-IDVVPEMLRWSFKIAAQTTMGSEVK 190
            |...:|:|....|...|.|......:|:..|....:|.| |::......:|..:...|:.|..:
Mouse   130 RTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFGAYSMDVITGTSCGVNI- 193

  Fly   191 HDEHFKN--GSLVESFESLISHSTLN-ILMPLVQNRMISKICGYDKLRADNFSRIQKMLDNVVNK 252
              :...|  ...|:..:.::.....: .|:.:|....::.|  |:.|....|.| |.|  |...|
Mouse   194 --DSLNNPQDPFVQKIKKILKFKFFDPFLLSVVLFPFLTPI--YEMLNLSIFPR-QSM--NFFKK 251

  Fly   253 KVNPLPKTDSDPESNIVINRA--MELY-----RKGD-----ITYMDVKSECCIMIAAGYDTSALT 305
            .|..:.|...|....   ||.  ::|.     .||.     ::.:::.::..|.|..|||.::.:
Mouse   252 FVKKMKKDRLDYNQK---NRVDFLQLMMNTQNSKGQESLKALSDLEMAAQTLIFIFGGYDGTSTS 313

  Fly   306 VYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLERVIKETLRLIPAIPITARE 370
            :...::.||.||:.|:.:.:|::...|:..  .:||..:..::||:.|:.|:|||.|.:....|.
Mouse   314 ISFIMYELATHPDVQKKLQDEIDRALPNKA--PVTYDALMDMEYLDMVVNESLRLYPVVSRIDRF 376

  Fly   371 TKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAENMEQKHPYAYIPFARGK 435
            :|.||.: :||.||||.::.|.::..||:||.| |:.::|.|:.|..||.....||.|:||..|.
Mouse   377 SKKDVEI-HGVFIPKGTIVMIPIYPLHRDPEYW-PEPEDFCPERFSKENKGNIDPYIYMPFGNGP 439

  Fly   436 RNCIGSKYAMMSSKFALCRILRNY------------KISTSTLYK 468
            |||||.::|::|.|.|:..:|:|:            |||...:::
Mouse   440 RNCIGMRFALISVKLAVTGVLQNFTVQPCEETQIPVKISRQPIFR 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	CYP313-like	66..487	CDD:410680	112/438 (26%)
Cyp3a57	NP_001093650.1	cytochrome_P450	67..492	CDD:477761	114/440 (26%)