Protein Alignment Cyp313a1 and CYP4F11

DIOPT Version :9

• Sequence 1: NP_650368.1
• Gene: Cyp313a1 / 41759
• FlyBaseID: FBgn0038236
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001122404.1
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 126/501 - (25%)
• Similarity: 210/501 - (41%)
• Gaps: 75/501 - (14%)

  Fly     6 LLLAVG-------ALFWIYFLWSRRRLYFLMLKIP------GPIGLPILGSSLENIITYKRKLSF 57
            |||.||       .|.|.|..:...|......:.|      |..||         :...:..:..
Human    21 LLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGHQGL---------VTPTEEGMKT 76

  Fly    58 RTKYLNKYGSTILTWMGPV-PFIVTRDPKVVEDIFS-SPDCHNKSQHIVNAITSCMGNGLLGKQD 120
            .|:.:..|......|:||. |.::...|.::..|.| |.....|.......:...:|:|||....
Human    77 LTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGG 141

  Fly   121 PHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKG--EIDVVPEMLRWSFKIAAQT 183
            ..|...|:...|:|..::|..:..||:....::.:.......:|  .:|:        |:..:..
Human   142 DKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDM--------FEHISLM 198

  Fly   184 TMGSEVKHDEHFKNGSLVESFESLISHSTLNILMPLVQ--------NRMI---SKICGYDKLRAD 237
            |:.|..|         .|.||||.........:..:::        |:.|   :....|......
Human   199 TLDSLQK---------CVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQ 254

  Fly   238 NFSR----IQKMLDNVVNKKVNPLPKTDSDPESNIVINRAME---------LYRKG----DITYM 285
            .|.|    :....|.|:.::...||....|   :.:.|:|..         |..|.    :::..
Human   255 RFRRACHLVHDFTDAVIQERRCTLPTQGID---DFLKNKAKSKTLDFIDVLLLSKDEDGKELSDE 316

  Fly   286 DVKSECCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYL 350
            |:::|....:..|:||:|..:...|:.||.|||:||...:|:..:..|.....|.:.|:.:|.:|
Human   317 DIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFL 381

  Fly   351 ERVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNF 415
            ...|||:|||.|.:|:.:|....|..|.:|.:||||:|..|::...|.||.|| ||.:.::|..|
Human   382 TMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVW-PDPEVYDPFRF 445

  Fly   416 LAENMEQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKI 461
            ..||::::.|.|:|||:.|.|||||..:||...|..|...|.:::|
Human   446 DQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRI 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	117/467 (25%)
CYP4F11	NP_001122404.1	p450	52..506	CDD:365848	117/470 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810