Protein Alignment Cyp313a1 and Cyp3a25

DIOPT Version :10

• Sequence 1: NP_650368.1
• Gene: Cyp313a1 / 41759
• FlyBaseID: FBgn0038236
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 488
• Identity: 126/488 - (25%)
• Similarity: 208/488 - (42%)
• Gaps: 68/488 - (13%)

  Fly     6 LLLAVGALFWIYFLWSRRRLYFLMLKIPGPIGLPILGSSLENIITYKRKLSFRTKYLNKYGSTIL 70
            ||:....||:||..:|..  .|..|.||||..||:||:...   .|.....|......|||....
Mouse    14 LLVTSLVLFYIYGTYSHG--LFKKLGIPGPKPLPLLGTIFN---YYDGMWKFDEDCYKKYGKIWG 73

  Fly    71 TWMGPVPFIVTRDPKVVEDIFSSPDCHN--KSQHIVNAITSCMGNGLLGKQDPHWLDRRKHFNPS 133
            .:.||.|.:...||:::: |....:|::  .::.....: ..|...:...:|..|...|...:|:
Mouse    74 FYEGPQPILAIMDPEIIK-IVLVKECYSVFTNRRFFGPV-GFMKKAITISEDEEWKRLRTLLSPT 136

  Fly   134 FKQDLLLSFFHIFDAETKVLMNLLDTYVDKGE-IDVVPEMLRWSFKIAAQTTMGSEV-----KHD 192
            |....|...|.|......:|:..|....:||| |.:......:|..:...|:.|..|     ..|
Mouse   137 FTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYSMDVITGTSFGVNVDSLNNPQD 201

  Fly   193 EHFKNGSLVESFE------------------------SLISHSTLNILMPLVQNRMISKICGYDK 233
            ...:....:..|:                        |:....::|.....|:.....::....|
Mouse   202 PFVQKAKKILKFKIFDPFLLSIILFPFLTPIYEMLNFSIFPRDSMNFFKKFVKRMKKERLASNQK 266

  Fly   234 LRADNFSRIQKMLDNVVNKKVNPLPKTDSDPESNIVINRAMELYRKGDITYMDVKSECCIMIAAG 298
            .|.|    ..:::.|..|.|.....|..||                     :::.::..|.|..|
Mouse   267 NRVD----FLQLMMNTQNSKGQESQKALSD---------------------LEMAAQAVIFIFGG 306

  Fly   299 YDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLERVIKETLRLIPA 363
            ||.::.::...::.||.||:.|:.:.:|::...|:..  .:||..:..::||:.|:.|:|||.|.
Mouse   307 YDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKA--PVTYDALMDMEYLDMVVNESLRLYPI 369

  Fly   364 IPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAENMEQKHPYAY 428
            .....|.:|.||.: |||.||||.|:.|.::..|||||.| |:...|.|:.|..||.....||.|
Mouse   370 AIRLERVSKKDVEI-NGVFIPKGTVVMIPIYPLHRNPEYW-PEPQEFCPERFSKENKGNIDPYIY 432

  Fly   429 IPFARGKRNCIGSKYAMMSSKFALCRILRNYKI 461
            :||..|.|||||.::|::|.|.|:..:|:|:.:
Mouse   433 MPFGNGPRNCIGMRFALISIKLAVIGVLQNFTV 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	CYP313-like	66..487	CDD:410680	105/428 (25%)
Cyp3a25	NP_062766.2	CYP3A	67..492	CDD:410743	107/430 (25%)