DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp313a1 and dib

DIOPT Version :9

Sequence 1:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_524810.2	Gene:	dib / 45282	FlyBaseID:	FBgn0000449	Length:	489	Species:	Drosophila melanogaster

Alignment Length:	461	Identity:	110/461 - (23%)
Similarity:	188/461 - (40%)	Gaps:	65/461 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 GPIGLPILGSSLENIITY---KRKLSFRTKYLNKYGSTILTWMGPVPFIV-TRDPKVVEDIFSSP 94
            ||.|:..|.:.|..|.:|   :...:.:.|| .|||:.:...:.|...|| ..|||.:..:.:..
  Fly    29 GPFGMGNLYNYLPGIGSYSWLRLHQAGQDKY-EKYGAIVRETIVPGQDIVWLYDPKDIALLLNER 92

  Fly    95 DCHNKSQHIVNA----------ITSCMGNGLLGKQDPHWLDRRKHFNPSFK-QDLLLSFFHIFDA 148
            ||..:..|:..|          .|:    |||....|.|...|........ ...:.:|....|.
  Fly    93 DCPQRRSHLALAQYRKSRPDVYKTT----GLLPTNGPEWWRIRAQVQKELSAPKSVRNFVRQVDG 153

  Fly   149 ETKVLMNLLDTYVDKGEIDVVPEMLRWSFKIAAQTTMGSEV------KHDEHFKNGSLVESFESL 207
            .||..:..|....:.|.||::|::.|.:.::....|.|:.:      :.|...::..|:::.|
  Fly   154 VTKEFIRFLQESRNGGAIDMLPKLTRLNLELTCLLTFGARLQSFTAQEQDPRSRSTRLMDAAE-- 216

  Fly   208 ISHSTLNILMPLVQNRMISKICGYDKLRADNFSRIQKMLDNVVNKKVNPLPKTDSDPESNIVINR 272
               :|.:.::|..|...:.:.......|  ..|:.|..:::|.      |...:.:..:..|.:.
  Fly   217 ---TTNSCILPTDQGLQLWRFLETPSFR--KLSQAQSYMESVA------LELVEENVRNGSVGSS 270

  Fly   273 AMELYRKG-DITYMDVKSECCIMIAAGYDT----SALTVYHALFLLANHPEHQEAVFEELNGVFP 332
            .:..|.|. ::...||......::.||.||    ||..:||    :|.:||.|:.:.||...|.|
  Fly   271 LISAYVKNPELDRSDVVGTAADLLLAGIDTTSYASAFLLYH----IARNPEVQQKLHEEARRVLP 331

  Fly   333 DAGHFGITYPDMQKLD-------YLERVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIG 390
            .|       .|...:|       |...|:||:|||.| |.:......|...:.:|..:|||..:.
  Fly   332 SA-------KDELSMDALRTDITYTRAVLKESLRLNP-IAVGVGRILNQDAIFSGYFVPKGTTVV 388

  Fly   391 IDMFHTHRNPEVWGPDADNFNPDNFLAENMEQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRI 455
            .......|..:.: .|...|.||.:| ::....:||..:||..|.|.||..:.|..:....|.|:
  Fly   389 TQNMVACRLEQHF-QDPLRFQPDRWL-QHRSALNPYLVLPFGHGMRACIARRLAEQNMHILLLRL 451

  Fly   456 LRNYKI 461
            ||.|::
  Fly   452 LREYEL 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	110/461 (24%)
dib	NP_524810.2	p450	25..446	CDD:299894	105/448 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010