DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a1 and Cyp4f4

DIOPT Version :9

Sequence 1:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_775146.1	Gene:	Cyp4f4 / 286904	RGDID:	708363	Length:	522	Species:	Rattus norvegicus

Alignment Length:	503	Identity:	140/503 - (27%)
Similarity:	225/503 - (44%)	Gaps:	79/503 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLLAVGALFWI--------YFLWSRRRLYFLMLKIPGPIGLP----ILGSSLENIITYKRKLSFR 58
            |||.:|| .|:        |..:   |.|..:...|.|   |    .|| .|..|...::.|...
  Rat    21 LLLLIGA-SWLLVRVLTQTYIFY---RTYQHLCDFPQP---PKWNWFLG-HLGMITPTEQGLKQV 77

  Fly    59 TKYLNKYGSTILTWMGPV-PFIVTRDPKVVEDIFS-SPDCHNKSQHIVNAITSCMGNGLLGKQDP 121
            ||.:..|....:||:||: |.|....|.|:..:.| |.....|.....:.:...:|:|||.....
  Rat    78 TKLVATYPQGFMTWLGPILPIITLCHPDVIRSVLSASASVALKEVIFYSFLKPWLGDGLLLSDGD 142

  Fly   122 HWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKG--EIDVVPEMLRWSFKIAAQTT 184
            .|...|:...|:|..::|..:..||:..|.::..........|  .:|:        ||..:..|
  Rat   143 KWSCHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQDLASGGSARLDM--------FKNISLMT 199

  Fly   185 MGS------------EVKHDEHFK-----NGSLVESFESLISHSTLNILMPLVQN-RMISKICGY 231
            :.|            :.|..|:..     :..:.:.::.|:.|:  :.|..|..| |...|.|
  Rat   200 LDSLQKCVFSFDSNCQEKPSEYISAILELSALVAKRYQQLLLHT--DSLYQLTHNGRRFHKAC-- 260

  Fly   232 DKLRADNFSRIQKMLDNVVNKKVNPLPKTDSDPESNIVINRAME---------LYRKG----DIT 283
             || ..||:      |.|:..:...||   |..|.:|:..:|..         |..|.    :::
  Rat   261 -KL-VHNFT------DAVIQGRRRALP---SQHEDDILKAKARSKTLDFIDVLLLTKDEDGKELS 314

  Fly   284 YMDVKSECCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLD 348
            ..|:::|....:..|:||:|..:...|:.||.|||:||...:|:..:..|.....|.:.|:.:|.
  Rat   315 DEDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRDRESTEIEWDDLAQLP 379

  Fly   349 YLERVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPD 413
            :|...|||:|||.|.:.:.:|....|:.|.:|.:|||||:..|::|.||.||.|| ||.:.::|.
  Rat   380 FLTMCIKESLRLHPPVTVISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVW-PDPEVYDPF 443

  Fly   414 NFLAENMEQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKI 461
            .|..||::.:.|.|:|||:.|.|||||..:||...|.||...|..:::
  Rat   444 RFDPENIKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFRV 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	131/468 (28%)
Cyp4f4	NP_775146.1	CYP4F	74..515	CDD:410772	124/442 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810