Protein Alignment Cyp313a1 and Cyp3a23-3a1

DIOPT Version :10

• Sequence 1: NP_650368.1
• Gene: Cyp313a1 / 41759
• FlyBaseID: FBgn0038236
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 527
• Identity: 144/527 - (27%)
• Similarity: 233/527 - (44%)
• Gaps: 89/527 - (16%)

  Fly     2 LTIN--LLLAVGALFWIYFLWSRRRLYFLMLKIPGPIGLPILGSSLENIITYKRKL-SFRTKYLN 63
            ||:.  :|||| .|..:|...:|....|....||||..||..|:    ::.|...| .|..:...
  Rat     7 LTLETWVLLAV-VLVLLYGFGTRTHGLFKKQGIPGPKPLPFFGT----VLNYYMGLWKFDVECHK 66

  Fly    64 KYGSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMGN-------GLLGK--- 118
            |||.....:.|.:|.....|.::::::            :|....|...|       |::||
  Rat    67 KYGKIWGLFDGQMPLFAITDTEMIKNV------------LVKECFSVFTNRRDFGPVGIMGKAIS 119

  Fly   119 --QDPHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGEIDVVPEML-RWSFKIA 180
              :|..|...|...:|:|....|...|.:.:....:|:..|..  :||:...|.|:. .:|..:.
  Rat   120 VSKDEEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQ--EKGKPVPVKEVFGAYSMDVI 182

  Fly   181 AQTTMGSEV--------KHDEHFKNGSLVESFESL-ISHSTLNILMPLVQNRMISKICGYDKLRA 236
            ..|:.|..|        ...|..|....::.|:.| :|......|.|:.:   :..||.:.|...
  Rat   183 TSTSFGVNVDSLNNPKDPFVEKAKKLLRIDFFDPLFLSVVLFPFLTPVYE---MLNICMFPKDSI 244

  Fly   237 DNFSRI-----QKMLDNVVNKKVNPL-----PKTDS-DPESNIVINRAMELYRKGDITYMDVKSE 290
            :.|.:.     :..||:|...:|:.|     ...|| |.||:..::.            |::.::
  Rat   245 EFFKKFVYRMKETRLDSVQKHRVDFLQLMMNAHNDSKDKESHTALSD------------MEITAQ 297

  Fly   291 CCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLERVIK 355
            ..|.|.|||:.::.|:...|..||.||:.|:.:.||::...|:..  ..||..:.:::||:.|:.
  Rat   298 SIIFIFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPNKA--PPTYDTVMEMEYLDMVLN 360

  Fly   356 ETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAENM 420
            |||||.|......|..|.||.: |||.:|||.|:.|..:..||:|:.| |:.:.|.|:.|..||.
  Rat   361 ETLRLYPIGNRLERVCKKDVEI-NGVFMPKGSVVMIPSYALHRDPQHW-PEPEEFRPERFSKENK 423

  Fly   421 EQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKISTSTLYKDLVYVDNMTMKLAEYPR 485
            ....||.|:||..|.|||||.::|:|:.|.||.::|:|:..              ...|..:.|
  Rat   424 GSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSF--------------QPCKETQIP- 473

  Fly   486 LKLQRRG 492
            |||.|:|
  Rat   474 LKLSRQG 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	CYP313-like	66..487	CDD:410680	117/453 (26%)
Cyp3a23-3a1	NP_037237.2	CYP3A	67..491	CDD:410743	124/462 (27%)