DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a1 and Cyp4f17

DIOPT Version :9

Sequence 1:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001094915.1	Gene:	Cyp4f17 / 208285	MGIID:	3646233	Length:	524	Species:	Mus musculus

Alignment Length:	491	Identity:	128/491 - (26%)
Similarity:	204/491 - (41%)	Gaps:	55/491 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLLAVGA-------LFWI---YFLWSRRRLYFLMLKIPGPIGLPILGSSLENIITYKRKLSFRTK 60
            ||..|||       |.||   |..:.|.|.:      |.|.........:..:...:..|...|:
Mouse    21 LLQLVGASLFLARILTWICAFYDNYCRLRCF------PEPPSRHWFWGHMSMVKNNEEGLQLLTE 79

  Fly    61 YLNKYGSTILTWMGP-VPFIVTRDPKVVEDIF-SSPDCHNKSQHIVNAITSCMGNGLLGKQDPHW 123
            ..:::....|.|:|| .|.:....||.:..|. :|.....|.......:...:|:|||......|
Mouse    80 RSHQFHDVHLCWIGPFYPILRLIHPKFIGPILQASAAVAPKEMIFYGFLKPWLGDGLLVSAGEKW 144

  Fly   124 LDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGEIDVVPEMLRWSFKIAAQTTMGSE 188
            ...|....|:|..|:|..:...|:....::.........||...:  :||.....:...:.....
Mouse   145 SRHRHLLTPAFHFDILKPYMKNFNKSVNIMHAKWQRLTTKGTACL--DMLEHISLMTLDSLQNCV 207

  Fly   189 VKHDEHFKNG-----SLVESFESLI---SHSTLNILMPL----VQNRMISKICGYDKLRADNFSR 241
            ...|.:.:..     :.::...|||   .|.....|..|    ...|...|.|..    ..||:
Mouse   208 FSFDSNCQESPSEYIAAIQELSSLIVKRHHQPFLYLDFLYYCTADGRRFRKACDL----VHNFT- 267

  Fly   242 IQKMLDNVVNKKVNPL----------PKTDSDPESNI-VINRAMELYRKGDITYMDVKSECCIMI 295
                 |.|:.::...|          .||.|.....| |:..|.:.:.| :::..|:::|....:
Mouse   268 -----DAVIRERRRTLSSQNLDEFLKSKTKSKTLDFIDVLLLAKDEHGK-ELSDEDIRAEADTFM 326

  Fly   296 AAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLERVIKETLRL 360
            ..|:||:|..:...|:.||.|||:||...:|:..:........|.:.|:.:|.:|...|||:|||
Mouse   327 FGGHDTTASALSWILYNLARHPEYQERCRQEVQELLRGREPQEIEWDDLAQLPFLTMCIKESLRL 391

  Fly   361 IPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAENMEQKHP 425
            .|.:.:.:|....||.|.:|.:||||....|.:|..|.||||| ||.:.::|..|..||.:::.|
Mouse   392 HPPVTVISRCCTQDVVLPDGRVIPKGTDCVISIFGVHHNPEVW-PDPEVYDPFRFDPENPQKRSP 455

  Fly   426 YAYIPFARGKRNCIGSKYAMMSSKFALCRILRNYKI 461
            .|:|||:.|.|||||..:||...|.||...|..:::
Mouse   456 LAFIPFSAGPRNCIGQTFAMREMKVALALTLLRFRV 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	117/454 (26%)
Cyp4f17	NP_001094915.1	p450	52..515	CDD:365848	117/454 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810