DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a1 and cyp-37B1

DIOPT Version :9

Sequence 1:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_507109.1	Gene:	cyp-37B1 / 180093	WormBaseID:	WBGene00009226	Length:	509	Species:	Caenorhabditis elegans

Alignment Length:	481	Identity:	144/481 - (29%)
Similarity:	242/481 - (50%)	Gaps:	47/481 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LFW---IY-FLWSRRRLYFLMLKIPGPIGLPILGS-SLENIITYKRKLSFRTK-------YLNKY 65
            ||:   || |:..|.|:|..|.|..||...||:|: .:.||....:   |.|:       |..|.
Worm    16 LFYYKLIYNFIRDRLRIYKYMRKFDGPYSFPIIGTLYMVNIFDISK---FTTQSMELAQYYCQKG 77

  Fly    66 GSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMGNGLLGKQDPHWLDRRKHF 130
            ..||..|:||||.|...:|:..::|..|.:...|::. .:.:...:|.|||......|..|||..
Worm    78 CGTIGLWLGPVPLIAVINPQHAKEILESNEVITKAEE-YDILFPWLGTGLLTSTGSKWRQRRKML 141

  Fly   131 NPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKG-EIDVVPEMLRWSFKIAAQTTMG----SEVK 190
            .|:|...:|..|..:.|.:.||.:..:..|.|.| |:|:.|.:.|.:..:...|:||    ::..
Worm   142 TPAFHFKVLNDFLSVHDYQAKVFLEQIKPYADSGKEVDLFPYIKRLALDVICDTSMGVTIDAQNN 206

  Fly   191 HDEHFKNGSLVESFESLISHSTLNILMPLVQNRMISKICG----YDKLRADNFSRIQKMLDNVVN 251
            ||..:     |||...|..::...||.|.::.:.:..:.|    ||:    :...:......|:.
Worm   207 HDHQY-----VESVRLLSEYAFEWILRPWLRLKPLWYLTGPGHEYDR----HLKIVTDFTKTVIK 262

  Fly   252 KK--------VNPLPKTDSDPESNIVINRAMELYRKGDITYMDVKSECCIMIAAGYDTSALTVYH 308
            :|        |:|:.|||.  .|...::..:||..:|.:...|::.|....:..|:||::.::..
Worm   263 EKWEEFQKFHVDPVVKTDK--RSMAFLDLLLELRNEGLMNEDDIREEVDTFMFEGHDTTSASMGW 325

  Fly   309 ALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKLDYLERVIKETLRLIPAIPITARETKN 373
            .|:.||::||.||.|.:|::|:|..:.. ..|..|::::.|||:.:||:||:.|::|...|..:.
Worm   326 TLWCLAHNPEFQEKVIQEVDGIFGTSDR-DCTNDDLKQMKYLEKCLKESLRMYPSVPFFGRTVEQ 389

  Fly   374 DVRLSNGVLIPKGVVIGIDMFHTHRNPEVWGPDADNFNPDNFLAENMEQKHPYAYIPFARGKRNC 438
            || :.||...||||.|.:......|||.:: .:.:.:||:||..:.:..:|.|:.|||:.|.|||
Worm   390 DV-VINGDFFPKGVRIIVMPLLLQRNPLIF-DNPNQYNPENFSEDKIGSRHAYSDIPFSAGPRNC 452

  Fly   439 IGSKYAMMSSKFALCRILRNYKISTS 464
            ||.|:|||..|..:....|.|:::.|
Worm   453 IGQKFAMMEEKAVISWFFRKYRVTAS 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	133/454 (29%)
cyp-37B1	NP_507109.1	p450	41..475	CDD:278495	133/451 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810