Protein Alignment Cyp313a1 and Cyp46a1

DIOPT Version :10

• Sequence 1: NP_650368.1
• Gene: Cyp313a1 / 41759
• FlyBaseID: FBgn0038236
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Alignment Length: 502
• Identity: 106/502 - (21%)
• Similarity: 199/502 - (39%)
• Gaps: 130/502 - (25%)

  Fly    37 GLPILGSSLENIITYKRKLSF----RTKYLNKYGSTILTW-MGPVPFIVTRDP---KVVEDIF-- 91
            ||.:|||::  ::.:....:|    |::|.:..|....:: :|.:|:...:|.   :|::|:|
Mouse     4 GLLLLGSAV--LLAFGLCCTFVHRARSRYEHIPGPPRPSFLLGHLPYFWKKDEDCGRVLQDVFLD 66

  Fly    92 ---------------------SSPDC---------HNKSQHIVNAITSCMGNGLLGK------QD 120
                                 :||:.         :||...:..|:.:..|..|.|:      ..
Mouse    67 WAKKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECDY 131

  Fly   121 PHWLDRRKHFNPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGE-------------IDVVPEM 172
            ..|..:||..:.:|.:..|:|....|:.:.:.|:.:|:...| |:             ||::.:.
Mouse   132 GRWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKAD-GQTPVSMQDMLTCATIDILAKA 195

  Fly   173 ---LRWSFKIAAQTTMGSEVKHDEHFKNGSLVESFESLISHSTLNILMPLVQNRMISKICGYDKL 234
               :..|..:.||..:...||        .::|...:  |.:||...||..:.::
Mouse   196 AFGMETSMLLGAQKPLSQAVK--------VMLEGISA--SRNTLAKFMPGKRKQL---------- 240

  Fly   235 RADNFSRIQKMLDNVVNKKVNPLPKTDSDPESNIVINRAMELYRKG-----DITYMDVKSE---- 290
                         ..:.:.:..|.:...|     .:.|..|..::|     ||....:|:|
Mouse   241 -------------REIRESIRLLRQVGKD-----WVQRRREALKRGEDMPADILTQILKAEEGAQ 287

  Fly   291 --------CCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFEELNGVFPDAGHFGITYPDMQKL 347
                    ......||::|||..:...:..|:..||....:..|::.|.....|  :.|.|:.:|
Mouse   288 DDEVLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRH--LDYEDLGRL 350

  Fly   348 DYLERVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIGIDMFHTH--RNPEVWGPDADNF 410
            .||.:|:||:|||.|....|.|..:.:. |.:||.:|....:   :|.|:  ...:.:..|...|
Mouse   351 QYLSQVLKESLRLYPPAWGTFRLLEEET-LIDGVRVPGNTPL---LFSTYVMGRMDTYFEDPLTF 411

  Fly   411 NPDNFLAENMEQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRILR 457
            |||.|  .....|..:.|.||:.|.|:|||.::|.|..|..:.::|:
Mouse   412 NPDRF--GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQ 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a1	NP_650368.1	CYP313-like	66..487	CDD:410680	98/469 (21%)
Cyp46a1	NP_034140.1	CYP46A1-like	61..484	CDD:410706	93/443 (21%)