Protein Alignment CG8461 and RRP36

DIOPT Version :10

• Sequence 1: NP_650367.1
• Gene: CG8461 / 41758
• FlyBaseID: FBgn0038235
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_149103.1
• Gene: RRP36 / 88745
• HGNCID: 21374
• Length: 259
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 79/230 - (34%)
• Similarity: 134/230 - (58%)
• Gaps: 23/230 - (10%)

  Fly    24 AIREDL----KGMSFEEIMKLKEELGAKVYKEAVLGSKSSRPQKPKAKTDLKR---LNKNRPREM 81
            |:..||    ..|||||:::|:.::|.|.||:.|.|:.   |:|..::..::.   .:|:||.||
Human    36 AVARDLLRGTSNMSFEELLELQSQVGTKTYKQLVAGNS---PKKQASRPPIQNACVADKHRPLEM 97

  Fly    82 TTRRQVPFLGAEHRVERKKNVELRDPRFDEKSGTYSAETFKKNYQFVSQIRAKEVGQLKKKLDEV 146
            :.:.:||||.....:.:|   ..||||||:.||.|:.|.|.|.|||::.|||||...:||:|.:.
Human    98 SAKIRVPFLRQVVPISKK---VARDPRFDDLSGEYNPEVFDKTYQFLNDIRAKEKELVKKQLKKH 159

  Fly   147 EDEAEKHHIKDTMQRLINKNVEDKKWHTKQKQ-----LKKERSAIQKKHDLGQQPHYLTKKERRA 206
            ....|...::..:||:..:.:..::  .||:|     ||:||.|..::   |.:|::|.|.|:|.
Human   160 LSGEEHEKLQQLLQRMEQQEMAQQE--RKQQQELHLALKQERRAQAQQ---GHRPYFLKKSEQRQ 219

  Fly   207 KELVAQFEKLKNTGKLNKHMEKRRKKNAAKDRKRI 241
            ..|..:|::||.:.||...:.::|::||.|||:.:
Human   220 LALAEKFKELKRSKKLENFLSRKRRRNAGKDRRHL 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8461	NP_650367.1	RRP36	72..232	CDD:461829	57/167 (34%)
RRP36	NP_149103.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		1/1 (100%)
		RRP36	91..245	CDD:461829	57/161 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	233..259		8/22 (36%)
		Nuclear localization signal. /evidence=ECO:0000255	241..244		0/2 (0%)