DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8461 and rrp36

DIOPT Version :9

Sequence 1:	NP_650367.1	Gene:	CG8461 / 41758	FlyBaseID:	FBgn0038235	Length:	244	Species:	Drosophila melanogaster
Sequence 2:	NP_001073413.1	Gene:	rrp36 / 321183	ZFINID:	ZDB-GENE-030131-9751	Length:	320	Species:	Danio rerio

Alignment Length:	249	Identity:	86/249 - (34%)
Similarity:	155/249 - (62%)	Gaps:	21/249 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSPSESSSASEHEASDDNETQN----AIREDLKGMSFEEIMKLKEELGAKVYKEAVLG-SKSSRP 61
            ::..|..|.||||...:::||:    .|:::|..|||||||.|:.::|.|||.:...| :|..:.
Zfish    77 AASDEDESDSEHEDEGNSKTQSHMEGNIKKELSTMSFEEIMALQNKVGTKVYNKIAYGDTKQKKK 141

  Fly    62 QKPKAKTDLKRLNKNRPREMTTRRQVPFLGAEHRVERKKNVELRDPRFDEKSGTYSAETFKKNYQ 126
            .:|     :|||||:||:|::::::||||   .:|...|.:..||||||:.||.|..|.|.:.|:
Zfish   142 NEP-----MKRLNKHRPQEISSKQRVPFL---RKVVPVKKMISRDPRFDDLSGEYKPEIFNQTYK 198

  Fly   127 FVSQIRAKEVGQLKKKLDEVEDEAEKHHIKDTMQRLIN-KNVEDKKWHTKQKQLKKERSAIQKKH 190
            |:..|:.||..:::|:|.:.:.:|::..:|..::|:.| :....::...::|:|:.:|    |:.
Zfish   199 FIKNIQEKEAQEVRKQLKKTKSKAKQEELKALLRRMDNQQRARQRQEQEREKELEFKR----KQR 259

  Fly   191 DL---GQQPHYLTKKERRAKELVAQFEKLKNTGKLNKHMEKRRKKNAAKDRKRI 241
            :|   |.:|.||.|.:::..||..::.:||.:|||...:.|:||:||.|||:::
Zfish   260 ELVGQGHKPFYLKKSDKKKLELAEKYSELKKSGKLENFLSKKRKRNATKDRRKL 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8461	NP_650367.1	DUF947	72..232	CDD:283706	54/163 (33%)
rrp36	NP_001073413.1	DUF947	147..304	CDD:283706	54/163 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595891
Domainoid	1	1.000	118	1.000	Domainoid score	I5851
eggNOG	1	0.900	-	-		E1_KOG3190
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40346
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4264
OMA	1	1.010	-	-		QHG55080
OrthoDB	1	1.010	-	-		D1471490at2759
OrthoFinder	1	1.000	-	-		FOG0005843
OrthoInspector	1	1.000	-	-		oto41233
orthoMCL	1	0.900	-	-		OOG6_103080
Panther	1	1.100	-	-	LDO	PTHR21738
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1216
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800