DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL11 and MRPL11

DIOPT Version :9

Sequence 1:	NP_524351.1	Gene:	mRpL11 / 41757	FlyBaseID:	FBgn0038234	Length:	196	Species:	Drosophila melanogaster
Sequence 2:	NP_057134.1	Gene:	MRPL11 / 65003	HGNCID:	14042	Length:	192	Species:	Homo sapiens

Alignment Length:	194	Identity:	80/194 - (41%)
Similarity:	121/194 - (62%)	Gaps:	9/194 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKAAGKLKSLKK-TVERVTHTSKLKTNIPAGMAAAGPPLGPMLGQRAINIAAFCKDFNAKTAEM 64
            |||.....:.|:| .|..|     ::..:.||:|..||||||:||||.::|..|||:||.:|.::
Human     1 MSKLGRAARGLRKPEVGGV-----IRAIVRAGLAMPGPPLGPVLGQRGVSINQFCKEFNERTKDI 60

  Fly    65 KEGVPLPCRISVNSDRSYDLAIHHPPATFFLKQAAGIQRGTMTPGKEVAGMITLKHLYEIAAIKI 129
            |||:|||.:|.|..||::::.|..|..::|||.||||::|....||||||::||||:||||.||.
Human    61 KEGIPLPTKILVKPDRTFEIKIGQPTVSYFLKAAAGIEKGARQTGKEVAGLVTLKHVYEIARIKA 125

  Fly   130 QDPPNVL--LTMQQMCEMLISIARTCGIKVVREIDPAAYGEFLEERKL-IVEQQRRELQEKREA 190
            ||....|  :.:..:...:|..||:.||:||:::.......|.:||.: :..|:..:|..:.||
Human   126 QDEAFALQDVPLSSVVRSIIGSARSLGIRVVKDLSSEELAAFQKERAIFLAAQKEADLAAQEEA 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL11	NP_524351.1	RL11	24..158	CDD:197819	64/135 (47%)
mRpL11	NP_524351.1	Ribosomal_L11	24..157	CDD:100101	64/134 (48%)
MRPL11	NP_057134.1	Ribosomal_L11	20..155	CDD:100101	64/134 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147650
Domainoid	1	1.000	74	1.000	Domainoid score	I9207
eggNOG	1	0.900	-	-		E1_COG0080
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6768
Inparanoid	1	1.050	149	1.000	Inparanoid score	I4395
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57720
OrthoDB	1	1.010	-	-		D1346532at2759
OrthoFinder	1	1.000	-	-		FOG0002852
OrthoInspector	1	1.000	-	-		oto89931
orthoMCL	1	0.900	-	-		OOG6_100842
Panther	1	1.100	-	-	LDO	PTHR11661
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1155
SonicParanoid	1	1.000	-	-		X1892
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800