Protein Alignment HtrA2 and DEG8

DIOPT Version :9

• Sequence 1: NP_001262565.1
• Gene: HtrA2 / 41756
• FlyBaseID: FBgn0038233
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_568575.1
• Gene: DEG8 / 833979
• AraportID: AT5G39830
• Length: 448
• Species: Arabidopsis thaliana
• Alignment Length: 408
• Identity: 116/408 - (28%)
• Similarity: 181/408 - (44%)
• Gaps: 98/408 - (24%)

  Fly    66 RFFVPFSLGAVVSAAIIQREDLTPTIAAS----KMTGRRRDFNFIADVVAGCADSVVYI------ 120
            |:....:||....|.:   ||::||:..:    ...||      |..:......|||.|
plant    84 RYLSALALGDPSVATV---EDVSPTVFPAGPLFPTEGR------IVQLFEKNTYSVVNIFDVTLR 139

  Fly   121 -EIKDTRHFDYFSGQPITASNGSGFIIEQNGLILTNAHVVIN------KPHTM---VQVRLSDG- 174
             ::|.|...:      |...||||.:.:..|.|:||.||:.|      .|..:   |.:..|||
plant   140 PQLKMTGVVE------IPEGNGSGVVWDGQGYIVTNYHVIGNALSRNPSPGDVVGRVNILASDGV 198

  Fly   175 -RTFPATIEDVDQTSDLATLRIQVNN--LSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVIS 236
             :.|...:...|:..|||.|::....  |..:::|:|::|:.|:..:|:|:|....:|:|.||||
plant   199 QKNFEGKLVGADRAKDLAVLKVDAPETLLKPIKVGQSNSLKVGQQCLAIGNPFGFDHTLTVGVIS 263

  Fly   237 STQRASQELGLRNRDI---------NYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVT-----A 287
                     || ||||         ..:||||||..|||||||::..|..||:|:...|     |
plant   264 ---------GL-NRDIFSQTGVTIGGGIQTDAAINPGNSGGPLLDSKGNLIGINTAIFTQTGTSA 318

  Fly   288 GISFAIPIDYVKVFLERAAEKRKKGSAYKTGYPVKRYMGITMLTLTPD-ILFELKSRSQNMPSNL 351
            |:.||||...|...:.:..:..|...|           ||. :.|.|| :..:|         |:
plant   319 GVGFAIPSSTVLKIVPQLIQFSKVLRA-----------GIN-IELAPDPVANQL---------NV 362

  Fly   352 THGVLVWKVIVGSPAHSGGLQP-----------GDIVTHINKKEIKNSSDVYDALADNS--KTLD 403
            .:|.||.:|...|.|...||.|           |||:..::.|.:||.:::...|.:.|  ..:.
plant   363 RNGALVLQVPGKSLAEKAGLHPTSRGFAGNIVLGDIIVAVDDKPVKNKAELMKILDEYSVGDKVT 427

  Fly   404 IVILRGVKQMHVTITPED 421
            :.|.||.:.:.:.|:.|:
plant   428 LKIKRGNEDLELKISLEE 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HtrA2	NP_001262565.1	DegQ	67..422	CDD:223343	115/407 (28%)
		Trypsin_2	141..280	CDD:290102	56/160 (35%)
		PDZ_serine_protease	323..417	CDD:238487	27/107 (25%)
DEG8	NP_568575.1	degP_htrA_DO	119..>445	CDD:273938	105/362 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D630723at2759
OrthoFinder	1	1.000	-	-		FOG0000153
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100391
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X265
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.680