Protein Alignment HtrA2 and DEG2

DIOPT Version :10

• Sequence 1: NP_650366.1
• Gene: HtrA2 / 41756
• FlyBaseID: FBgn0038233
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_566115.1
• Gene: DEG2 / 819406
• AraportID: AT2G47940
• Length: 607
• Species: Arabidopsis thaliana
• Alignment Length: 253
• Identity: 89/253 - (35%)
• Similarity: 123/253 - (48%)
• Gaps: 40/253 - (15%)

  Fly   139 SNGSGFIIEQNGLILTNAHVVINKPHTMVQV-RLSDGRTFPA--TIEDVDQTSDLATLRIQVNNL 200
            |.||.|:| .:|.:|||||.|  :..|.|:| |..|.|.:.|  .:..||  .|:|.|.::..:.
plant   142 STGSAFMI-GDGKLLTNAHCV--EHDTQVKVKRRGDDRKYVAKVLVRGVD--CDIALLSVESEDF 201

  Fly   201 ----SVMRLGKSSTLRSGEWVVALGSPLALSN-TVTAGVISSTQRASQELGLRNRDINYLQTDAA 260
                ..:|||....|:..  |..:|.||.... :||.||:|..:..|...|  :.|:..:|.|||
plant   202 WKGAEPLRLGHLPRLQDS--VTVVGYPLGGDTISVTKGVVSRIEVTSYAHG--SSDLLGIQIDAA 262

  Fly   261 ITFGNSGGPLVNLDGEAIGVNSMKV-----TAGISFAIPIDYVKVFLERAAEKRKKGSAYKTGYP 320
            |..||||||..|..||.||| :.:|     |..|.:.||...|..||   .:..:.|.  .||||
plant   263 INPGNSGGPAFNDQGECIGV-AFQVYRSEETENIGYVIPTTVVSHFL---TDYERNGK--YTGYP 321

  Fly   321 VKRYMGITMLTLTPDILFE-LKSRSQNMPSNLTHGVLVWKVIVGSPAHSGGLQPGDIV 377
            .   :|:.:..|....|.| ||     :|:|  .||||.:|...|.| |..|:.||::
plant   322 C---LGVLLQKLENPALRECLK-----VPTN--EGVLVRRVEPTSDA-SKVLKEGDVI 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HtrA2	NP_650366.1	DegQ	141..421	CDD:440035	88/251 (35%)
DEG2	NP_566115.1	DegQ	142..425	CDD:440035	89/253 (35%)
		PDZ_3	429..570	CDD:436064