Protein Alignment HtrA2 and si:dkey-84o3.7

DIOPT Version :9

• Sequence 1: NP_001262565.1
• Gene: HtrA2 / 41756
• FlyBaseID: FBgn0038233
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_017208436.1
• Gene: si:dkey-84o3.7 / 799634
• ZFINID: ZDB-GENE-091113-30
• Length: 200
• Species: Danio rerio
• Alignment Length: 206
• Identity: 104/206 - (50%)
• Similarity: 153/206 - (74%)
• Gaps: 14/206 - (6%)

  Fly   220 LGSPLALSNTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMK 284
            :|||.:|.||:|:|::||.||.|:||||.|.:::|:||||.|.||||||||:|||||.|.:|:||
Zfish     1 MGSPFSLKNTITSGIVSSAQRGSKELGLSNSNMDYIQTDATIDFGNSGGPLINLDGEVIDINTMK 65

  Fly   285 VTAGISFAIPIDYVKVFLERAAEKRKK---GSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQN 346
            ||||||||||.|.|::||:|:|:|:|.   .|.:|     :||:|:.||||||.|:.||:.|.
Zfish    66 VTAGISFAIPSDRVRLFLDRSADKQKSWFGESGWK-----RRYIGVMMLTLTPSIIEELRMRD-- 123

  Fly   347 MPS--NLTHGVLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRG 409
             ||  ::.||||:.:|||||||:..|::|||::..||..::..|.::|:|:. .|::|::|:.||
Zfish   124 -PSFHDVFHGVLIHRVIVGSPANRAGMKPGDVIIEINGVKVNTSEEIYNAVR-TSESLNVVVRRG 186

  Fly   410 VKQMHVTITPE 420
            ...:.:.:|||
Zfish   187 ADLLMLHMTPE 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HtrA2	NP_001262565.1	DegQ	67..422	CDD:223343	104/206 (50%)
		Trypsin_2	141..280	CDD:290102	38/59 (64%)
		PDZ_serine_protease	323..417	CDD:238487	40/95 (42%)
si:dkey-84o3.7	XP_017208436.1	Trypsin_2	<1..59	CDD:290102	37/57 (65%)
		PDZ_serine_protease	102..186	CDD:238487	38/87 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579594
Domainoid	1	1.000	47	1.000	Domainoid score	I11974
eggNOG	1	0.900	-	-		E1_COG0265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H113300
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D238833at33208
OrthoFinder	1	1.000	-	-		FOG0000153
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.710