Protein Alignment HtrA2 and si:dkey-19p15.4

DIOPT Version :9

• Sequence 1: NP_001262565.1
• Gene: HtrA2 / 41756
• FlyBaseID: FBgn0038233
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_021336616.1
• Gene: si:dkey-19p15.4 / 797876
• ZFINID: ZDB-GENE-081028-23
• Length: 260
• Species: Danio rerio
• Alignment Length: 241
• Identity: 138/241 - (57%)
• Similarity: 189/241 - (78%)
• Gaps: 12/241 - (4%)

  Fly   131 FSGQPITASNGSGFIIEQNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRI 195
            |||:.:..||||||||..:.||:||||||.|||.  |:|:|::|.|:.||::||||.:|:||::|
Zfish    23 FSGREVPISNGSGFIISSDDLIVTNAHVVANKPG--VRVKLTNGETYNATVQDVDQAADIATIKI 85

  Fly   196 QVNN-LSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVISSTQRASQELGLRNRDINYLQTDA 259
            .|.| |..:||||||.:|.||:|||:|||.:|.||:|:|::||.||.|:||||.|.:::|:||||
Zfish    86 NVKNPLPTLRLGKSSDVRQGEFVVAMGSPFSLKNTITSGIVSSAQRGSKELGLSNSNMDYIQTDA 150

  Fly   260 AITFGNSGGPLVNLDGEAIGVNSMKVTAGISFAIPIDYVKVFLERAAEKRKK---GSAYKTGYPV 321
            .|.||||||||:|||||.||:|:||||||||||||.|.|::||:|:|:|:..   .|.:|
Zfish   151 TIDFGNSGGPLINLDGEVIGINTMKVTAGISFAIPSDRVRLFLDRSADKQNSWFGESGWK----- 210

  Fly   322 KRYMGITMLTLTPDILFELKSRSQNMPSNLTHGVLVWKVIVGSPAH 367
            :||:|:.||||||.|:.||:.|..:.| :::||||:.:|||||||:
Zfish   211 RRYIGVMMLTLTPSIIEELRMRDPSFP-DVSHGVLIHRVIVGSPAN 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HtrA2	NP_001262565.1	DegQ	67..422	CDD:223343	138/241 (57%)
		Trypsin_2	141..280	CDD:290102	85/139 (61%)
		PDZ_serine_protease	323..417	CDD:238487	25/45 (56%)
si:dkey-19p15.4	XP_021336616.1	DegQ	22..>256	CDD:333159	138/241 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	70	1.000	Domainoid score	I9474
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H113300
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D238833at33208
OrthoFinder	1	1.000	-	-		FOG0000153
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920