Protein Alignment HtrA2 and Tysnd1

DIOPT Version :10

• Sequence 1: NP_650366.1
• Gene: HtrA2 / 41756
• FlyBaseID: FBgn0038233
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_082188.1
• Gene: Tysnd1 / 71767
• MGIID: 1919017
• Length: 568
• Species: Mus musculus
• Alignment Length: 209
• Identity: 50/209 - (23%)
• Similarity: 90/209 - (43%)
• Gaps: 43/209 - (20%)

  Fly   141 GSGFIIEQNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIEDV----------DQTS--DLATL 193
            |||.::... |::|..||.   |....:|.:..     ||.::|          .:||  |:|.:
Mouse   359 GSGVVVAPR-LVVTCRHVA---PREAARVLVHS-----ATPKNVAIWGQVVFATQETSPYDIAVV 414

  Fly   194 RIQVNNLSVMRLGKSSTLRSGEWVVALGSPL---ALSNTVTAGVISSTQRASQELGLRNRDINYL 255
            .::.....|.....:.....||.|..:|..:   |...:||:|::|:..|......:       |
Mouse   415 SLEEELNGVPTPVPAGHFHEGEPVSVVGFGVFGQACGPSVTSGILSAVVRVDGSPVM-------L 472

  Fly   256 QTDAAITFGNSGGPLVNL-DGEAIGV---NSMKVTAG-----ISFAIPIDYVKVFLERAAEKRKK 311
            ||..|:..|:|||||.:. .|:.:|:   |:.....|     ::|:|||..::..|::.::....
Mouse   473 QTTCAVHGGSSGGPLFSSGSGDLLGIVASNTRDNNTGATYPHLNFSIPITVLQPALKQYSQTGDL 537

  Fly   312 GSAYK---TGYPVK 322
            |...:   |..||:
Mouse   538 GGLRELDHTTEPVR 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HtrA2	NP_650366.1	DegQ	141..421	CDD:440035	50/209 (24%)
Tysnd1	NP_082188.1	Trypsin_2	359..498	CDD:433149	38/154 (25%)