Protein Alignment HtrA2 and htra3b

DIOPT Version :10

• Sequence 1: NP_650366.1
• Gene: HtrA2 / 41756
• FlyBaseID: FBgn0038233
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: XP_073763543.1
• Gene: htra3b / 573378
• ZFINID: ZDB-GENE-110602-1
• Length: 466
• Species: Danio rerio
• Alignment Length: 326
• Identity: 146/326 - (44%)
• Similarity: 219/326 - (67%)
• Gaps: 14/326 - (4%)

  Fly   100 RRDFNFIADVVAGCADSVVYIEIKDTRHFDYFSGQPITASNGSGFIIEQNGLILTNAHVVIN--- 161
            |..||||||||...|.:||:||:  ..:...| |:.:..|:||||::.:.|||:||||||.:
Zfish   146 RYKFNFIADVVEKIAPAVVHIEL--FLNHPLF-GRTVPLSSGSGFVMSETGLIVTNAHVVSSTTS 207

  Fly   162 -KPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQ-VNNLSVMRLGKSSTLRSGEWVVALGSPL 224
             ..|..::|::.||..:.|||:|:|:.||:||::|. ...|.|:.||.|:.||.||:|||:|||.
Zfish   208 VSGHQRLKVQMRDGDVYEATIQDIDKKSDIATIKINPQKKLPVLLLGHSADLRPGEFVVAIGSPF 272

  Fly   225 ALSNTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVTAGI 289
            ||.||||.|::|:.||..:||||::.|::|:||||.|.:|||||||||||||.||:|::||.|||
Zfish   273 ALQNTVTTGIVSTAQRDGKELGLQDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGI 337

  Fly   290 SFAIPIDYVKVFLERAAEKRKKGSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPSNLTHG 354
            |||||.|.:..||..:..|:.|    :|....||::||.|||:|..::.|||.::.:.| :::.|
Zfish   338 SFAIPSDRITRFLNDSLGKQNK----ETRSVKKRFIGIRMLTITDALVEELKQQNPDFP-DVSSG 397

  Fly   355 VLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRGVKQMHVTITP 419
            :.|.:|:..|||..||::.|||:..:|.:.:.::||:.:|| :...||.:.:.||...:...|.|
Zfish   398 IFVHEVVPHSPAQKGGIRDGDIIVKLNGEPLLSTSDLKEAL-NQDMTLLLEVRRGNDDLLFNIEP 461

  Fly   420 E 420
            :
Zfish   462 D 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HtrA2	NP_650366.1	DegQ	141..421	CDD:440035	129/285 (45%)
htra3b	XP_073763543.1	None