Protein Alignment HtrA2 and PSMD9

DIOPT Version :9

• Sequence 1: NP_001262565.1
• Gene: HtrA2 / 41756
• FlyBaseID: FBgn0038233
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_002804.2
• Gene: PSMD9 / 5715
• HGNCID: 9567
• Length: 223
• Species: Homo sapiens
• Alignment Length: 213
• Identity: 44/213 - (20%)
• Similarity: 79/213 - (37%)
• Gaps: 47/213 - (22%)

  Fly   232 AGVISSTQRASQELGLRNRDI------NY--LQTDAAITFGNSGGPLVNLDG---EAIGVNSMKV 285
            |||:  |....|||..|..:|      ||  |::...|....   |||:.:|   ..:.:..::.
Human    15 AGVV--TVSDVQELMRRKEEIEAQIKANYDVLESQKGIGMNE---PLVDCEGYPRSDVDLYQVRT 74

  Fly   286 TAGISFAIPIDYVKVFLE----------RAAEKRKKGSAYKTGYPVKRYMGITMLTLTPDILFEL 340
            .......:..|:..|..:          |..||:.:..|......:.|.:|
Human    75 ARHNIICLQNDHKAVMKQVEEALHQLHARDKEKQARDMAEAHKEAMSRKLG-------------- 125

  Fly   341 KSRSQNMPSNLTHGVLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYD--ALADNS--KT 401
            :|.||..|.....   |..:..||||...|||..|.:........:|...:::  ::..:|  |.
Human   126 QSESQGPPRAFAK---VNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQSLHNIGSVVQHSEGKP 187

  Fly   402 LDIVILRGVKQMHVTITP 419
            |::.::|..::..:.:.|
Human   188 LNVTVIRRGEKHQLRLVP 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HtrA2	NP_001262565.1	DegQ	67..422	CDD:223343	44/213 (21%)
		Trypsin_2	141..280	CDD:290102	17/58 (29%)
		PDZ_serine_protease	323..417	CDD:238487	20/97 (21%)
PSMD9	NP_002804.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	103..141		11/54 (20%)
		PDZ_metalloprotease	129..205	CDD:238489	17/78 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900