DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HtrA2 and psmd-9

DIOPT Version :9

Sequence 1:	NP_001262565.1	Gene:	HtrA2 / 41756	FlyBaseID:	FBgn0038233	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001379558.1	Gene:	psmd-9 / 24104302	WormBaseID:	WBGene00016623	Length:	197	Species:	Caenorhabditis elegans

Alignment Length:	106	Identity:	21/106 - (19%)
Similarity:	43/106 - (40%)	Gaps:	17/106 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   332 LTPDILFELKSR----------SQNMPSNLTHG---VLVWKVIVGSPAHSGGLQPGDIVTHINKK 383
            ||..|:.|:::.          |:..|.:.|..   |.:..|:..|||..||.:..|::......
Worm    72 LTEKIVVEMENENKEVSGQTATSEEKPVHRTSNEPFVKISSVVELSPADIGGFRKDDLIIQYGNL 136

  Fly   384 EIKNSSDVYDAL----ADNSKTLDIVILRGVKQMHVTITPE 420
            ...|.:|:.:..    ....|.:.:.::|..:.:.:.|.|:
Worm   137 HHGNFNDMQEVAQITKQSEDKIIRVTVIRENRPVRLEICPK 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HtrA2	NP_001262565.1	DegQ	67..422	CDD:223343	21/106 (20%)
		Trypsin_2	141..280	CDD:290102
		PDZ_serine_protease	323..417	CDD:238487	19/101 (19%)
psmd-9	NP_001379558.1	Nas2_N	7..81	CDD:408080	4/8 (50%)
psmd-9	NP_001379558.1	PDZ_6	110..165	CDD:407688	10/54 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0265
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900