| Sequence 1: | NP_001262565.1 | Gene: | HtrA2 / 41756 | FlyBaseID: | FBgn0038233 | Length: | 422 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_710159.1 | Gene: | HTRA4 / 203100 | HGNCID: | 26909 | Length: | 476 | Species: | Homo sapiens |
| Alignment Length: | 328 | Identity: | 147/328 - (44%) |
|---|---|---|---|
| Similarity: | 217/328 - (66%) | Gaps: | 25/328 - (7%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 100 RRDFNFIADVVAGCADSVVYIEIKDTRHFDYFSGQPITAS------NGSGFIIEQNGLILTNAHV 158
Fly 159 VINKPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQVN-NLSVMRLGKSSTLRSGEWVVALGS 222
Fly 223 PLALSNTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVTA 287
Fly 288 GISFAIPIDYVKVFLERAAEKRKKGSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPSNLT 352
Fly 353 HGVLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRGVKQMHVTI 417
Fly 418 TPE 420 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HtrA2 | NP_001262565.1 | DegQ | 67..422 | CDD:223343 | 147/328 (45%) |
| Trypsin_2 | 141..280 | CDD:290102 | 74/139 (53%) | ||
| PDZ_serine_protease | 323..417 | CDD:238487 | 34/93 (37%) | ||
| HTRA4 | NP_710159.1 | IGFBP | 40..94 | CDD:278641 | |
| Kazal_2 | 108..152 | CDD:284958 | |||
| DegQ | 156..470 | CDD:223343 | 144/323 (45%) | ||
| Serine protease | 202..362 | 89/161 (55%) | |||
| Trypsin_2 | 202..340 | CDD:290102 | 74/139 (53%) | ||
| PDZ_serine_protease | 380..470 | CDD:238487 | 34/92 (37%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 166 | 1.000 | Domainoid score | I3884 |
| eggNOG | 1 | 0.900 | - | - | E1_COG0265 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D238833at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000153 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100391 | |
| Panther | 1 | 1.100 | - | - | O | PTHR22939 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X265 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 9 | 8.780 | |||||